The Caenorhabditis elegans cullin-RING ubiquitin ligase CRL4DCAF-1 is required for proper germline nucleolus morphology and male development

Abstract Cullin-RING ubiquitin ligases (CRLs) are the largest class of ubiquitin ligases with diverse functions encompassing hundreds of cellular processes. Inactivation of core components of the CRL4 ubiquitin ligase produces a germ cell defect in Caenorhabditis elegans that is marked by abnormal g...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genetics (Austin) 2023-08, Vol.225 (1)
Hauptverfasser:	Rahman, Mohammad M, Balachandran, Riju S, Stevenson, Jonathan B, Kim, Youngjo, Proenca, Rui B, Hedgecock, Edward M, Kipreos, Edward T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biosynthesis Caenorhabditis elegans Caenorhabditis elegans - genetics Caenorhabditis elegans - metabolism Cell Nucleolus - genetics Cell Nucleolus - metabolism Cullin Cullin Proteins - genetics Cullin Proteins - metabolism Cytology Deactivation Defects Embryos Epitopes Fog Germ cells Germ Cells - metabolism Hypodermis Inactivation Intestine Investigation Larvae Lethality Male Males Mice Morphology Mutants Nematodes Nucleoli Proteins Ribonucleic acid Ribosomes RNA RNA-mediated interference Semen - metabolism Substrates Transcription Factors - genetics Transmission electron microscopy Ubiquitin - metabolism Ubiquitin-protein ligase
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!