Nerve stimulation for the treatment of obstructive sleep apnea

This review will trace the elements of neurostimulation for obstructive sleep apnea and details on its implementation, efficacy and safety, immediate clinical outcomes, and future prospects. The literature on upper airway neurostimulation was surveyed from July 2013 to July 2019, with a focus on the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sleep and biological rhythms 2020, Vol.18 (2), p.77-87
Hauptverfasser: Yamauchi, Motoo, Satoh, Makoto, Kitahara, Tadashi, Ota, Ichiro, Strohl, Kingman
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 87
container_issue 2
container_start_page 77
container_title Sleep and biological rhythms
container_volume 18
creator Yamauchi, Motoo
Satoh, Makoto
Kitahara, Tadashi
Ota, Ichiro
Strohl, Kingman
description This review will trace the elements of neurostimulation for obstructive sleep apnea and details on its implementation, efficacy and safety, immediate clinical outcomes, and future prospects. The literature on upper airway neurostimulation was surveyed from July 2013 to July 2019, with a focus on the components of devices, evidence for clinical utility, and adverse events. Current technology is focused on the hypoglossal nerve stimulation (HNS). The most long-term experience is with the Inspire Medical System (Maple Grove, MN USA) which has both FDA and European regulatory approval. Given the inclusion criteria- BMI 
doi_str_mv 10.1007/s41105-020-00252-2
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10686243</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2895711008</sourcerecordid><originalsourceid>FETCH-LOGICAL-c497t-ac9cf3edb8db33612748446f9b71e20458e0ccf6ace2f56126ded914658314173</originalsourceid><addsrcrecordid>eNp9kE1LxDAURYMoOI7-AVdduqnms003igx-waAbXYc0fZnp0DY1SQf892acQXDjKg_euTePg9AlwdcE4_ImcEKwyDHFOcZU0JweoRnhZZVLTsXxbuZFXlEmTtFZCJsEccHoDN2-gt9CFmLbT52OrRsy63wW15BFDzr2MMTM2czVIfrJxHYHdwBjpscB9Dk6sboLcHF45-jj8eF98Zwv355eFvfL3PCqjLk2lbEMmlo2NWMFoSWX6SBb1SUBirmQgI2xhTZArUj7ooGmIrwQkhFOSjZHd_vecap7aEy6yutOjb7ttf9STrfq72Zo12rltorgQhaUs9RwdWjw7nOCEFXfBgNdpwdwU1BUVqJMErFMKN2jxrsQPNjffwhWO91qr1sl3epHt6IpxPahkOBhBV5t3OSHJOW_1DfCzYPR</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2895711008</pqid></control><display><type>article</type><title>Nerve stimulation for the treatment of obstructive sleep apnea</title><source>SpringerLink Journals</source><creator>Yamauchi, Motoo ; Satoh, Makoto ; Kitahara, Tadashi ; Ota, Ichiro ; Strohl, Kingman</creator><creatorcontrib>Yamauchi, Motoo ; Satoh, Makoto ; Kitahara, Tadashi ; Ota, Ichiro ; Strohl, Kingman</creatorcontrib><description>This review will trace the elements of neurostimulation for obstructive sleep apnea and details on its implementation, efficacy and safety, immediate clinical outcomes, and future prospects. The literature on upper airway neurostimulation was surveyed from July 2013 to July 2019, with a focus on the components of devices, evidence for clinical utility, and adverse events. Current technology is focused on the hypoglossal nerve stimulation (HNS). The most long-term experience is with the Inspire Medical System (Maple Grove, MN USA) which has both FDA and European regulatory approval. Given the inclusion criteria- BMI &lt; 35 (ideally &lt; 32), AHI 15–65/h, and a favorable anterior–posterior velopharyngeal collapse pattern on DISE, across many centers ~ 65% of patients who are intolerant to primary therapy achieve clinical success (AHI &lt; 20/h with a reduction of &lt; 50% in AHI), and more have symptomatic relief. Adverse events are generally mild, often self-limited, with occasional need for uncomplicated surgical adjustments or replacement of the implantable generator. Three other devices are in various phases of development, each with differences in nerve electrodes, implantable components, power sources, proprietary programming, and activation patterns. Hypoglossal nerve stimulation (HNS) is not considered a first-line treatment option. HNS therapy, however, should be considered as one alternative therapeutic option for patients meeting the inclusion criteria when more traditional therapeutic options have been considered.</description><identifier>ISSN: 1446-9235</identifier><identifier>EISSN: 1479-8425</identifier><identifier>DOI: 10.1007/s41105-020-00252-2</identifier><language>eng</language><publisher>Tokyo: Springer Japan</publisher><subject>Biomedical and Life Sciences ; Biomedicine ; Health Psychology ; Human Physiology ; Internal Medicine ; Neurology ; Neurosciences ; Psychiatry ; Review Article</subject><ispartof>Sleep and biological rhythms, 2020, Vol.18 (2), p.77-87</ispartof><rights>Japanese Society of Sleep Research 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c497t-ac9cf3edb8db33612748446f9b71e20458e0ccf6ace2f56126ded914658314173</citedby><cites>FETCH-LOGICAL-c497t-ac9cf3edb8db33612748446f9b71e20458e0ccf6ace2f56126ded914658314173</cites><orcidid>0000-0001-7740-9013</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s41105-020-00252-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s41105-020-00252-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,776,780,881,27903,27904,41467,42536,51298</link.rule.ids></links><search><creatorcontrib>Yamauchi, Motoo</creatorcontrib><creatorcontrib>Satoh, Makoto</creatorcontrib><creatorcontrib>Kitahara, Tadashi</creatorcontrib><creatorcontrib>Ota, Ichiro</creatorcontrib><creatorcontrib>Strohl, Kingman</creatorcontrib><title>Nerve stimulation for the treatment of obstructive sleep apnea</title><title>Sleep and biological rhythms</title><addtitle>Sleep Biol. Rhythms</addtitle><description>This review will trace the elements of neurostimulation for obstructive sleep apnea and details on its implementation, efficacy and safety, immediate clinical outcomes, and future prospects. The literature on upper airway neurostimulation was surveyed from July 2013 to July 2019, with a focus on the components of devices, evidence for clinical utility, and adverse events. Current technology is focused on the hypoglossal nerve stimulation (HNS). The most long-term experience is with the Inspire Medical System (Maple Grove, MN USA) which has both FDA and European regulatory approval. Given the inclusion criteria- BMI &lt; 35 (ideally &lt; 32), AHI 15–65/h, and a favorable anterior–posterior velopharyngeal collapse pattern on DISE, across many centers ~ 65% of patients who are intolerant to primary therapy achieve clinical success (AHI &lt; 20/h with a reduction of &lt; 50% in AHI), and more have symptomatic relief. Adverse events are generally mild, often self-limited, with occasional need for uncomplicated surgical adjustments or replacement of the implantable generator. Three other devices are in various phases of development, each with differences in nerve electrodes, implantable components, power sources, proprietary programming, and activation patterns. Hypoglossal nerve stimulation (HNS) is not considered a first-line treatment option. HNS therapy, however, should be considered as one alternative therapeutic option for patients meeting the inclusion criteria when more traditional therapeutic options have been considered.</description><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Health Psychology</subject><subject>Human Physiology</subject><subject>Internal Medicine</subject><subject>Neurology</subject><subject>Neurosciences</subject><subject>Psychiatry</subject><subject>Review Article</subject><issn>1446-9235</issn><issn>1479-8425</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LxDAURYMoOI7-AVdduqnms003igx-waAbXYc0fZnp0DY1SQf892acQXDjKg_euTePg9AlwdcE4_ImcEKwyDHFOcZU0JweoRnhZZVLTsXxbuZFXlEmTtFZCJsEccHoDN2-gt9CFmLbT52OrRsy63wW15BFDzr2MMTM2czVIfrJxHYHdwBjpscB9Dk6sboLcHF45-jj8eF98Zwv355eFvfL3PCqjLk2lbEMmlo2NWMFoSWX6SBb1SUBirmQgI2xhTZArUj7ooGmIrwQkhFOSjZHd_vecap7aEy6yutOjb7ttf9STrfq72Zo12rltorgQhaUs9RwdWjw7nOCEFXfBgNdpwdwU1BUVqJMErFMKN2jxrsQPNjffwhWO91qr1sl3epHt6IpxPahkOBhBV5t3OSHJOW_1DfCzYPR</recordid><startdate>2020</startdate><enddate>2020</enddate><creator>Yamauchi, Motoo</creator><creator>Satoh, Makoto</creator><creator>Kitahara, Tadashi</creator><creator>Ota, Ichiro</creator><creator>Strohl, Kingman</creator><general>Springer Japan</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-7740-9013</orcidid></search><sort><creationdate>2020</creationdate><title>Nerve stimulation for the treatment of obstructive sleep apnea</title><author>Yamauchi, Motoo ; Satoh, Makoto ; Kitahara, Tadashi ; Ota, Ichiro ; Strohl, Kingman</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c497t-ac9cf3edb8db33612748446f9b71e20458e0ccf6ace2f56126ded914658314173</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Health Psychology</topic><topic>Human Physiology</topic><topic>Internal Medicine</topic><topic>Neurology</topic><topic>Neurosciences</topic><topic>Psychiatry</topic><topic>Review Article</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yamauchi, Motoo</creatorcontrib><creatorcontrib>Satoh, Makoto</creatorcontrib><creatorcontrib>Kitahara, Tadashi</creatorcontrib><creatorcontrib>Ota, Ichiro</creatorcontrib><creatorcontrib>Strohl, Kingman</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Sleep and biological rhythms</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yamauchi, Motoo</au><au>Satoh, Makoto</au><au>Kitahara, Tadashi</au><au>Ota, Ichiro</au><au>Strohl, Kingman</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nerve stimulation for the treatment of obstructive sleep apnea</atitle><jtitle>Sleep and biological rhythms</jtitle><stitle>Sleep Biol. Rhythms</stitle><date>2020</date><risdate>2020</risdate><volume>18</volume><issue>2</issue><spage>77</spage><epage>87</epage><pages>77-87</pages><issn>1446-9235</issn><eissn>1479-8425</eissn><abstract>This review will trace the elements of neurostimulation for obstructive sleep apnea and details on its implementation, efficacy and safety, immediate clinical outcomes, and future prospects. The literature on upper airway neurostimulation was surveyed from July 2013 to July 2019, with a focus on the components of devices, evidence for clinical utility, and adverse events. Current technology is focused on the hypoglossal nerve stimulation (HNS). The most long-term experience is with the Inspire Medical System (Maple Grove, MN USA) which has both FDA and European regulatory approval. Given the inclusion criteria- BMI &lt; 35 (ideally &lt; 32), AHI 15–65/h, and a favorable anterior–posterior velopharyngeal collapse pattern on DISE, across many centers ~ 65% of patients who are intolerant to primary therapy achieve clinical success (AHI &lt; 20/h with a reduction of &lt; 50% in AHI), and more have symptomatic relief. Adverse events are generally mild, often self-limited, with occasional need for uncomplicated surgical adjustments or replacement of the implantable generator. Three other devices are in various phases of development, each with differences in nerve electrodes, implantable components, power sources, proprietary programming, and activation patterns. Hypoglossal nerve stimulation (HNS) is not considered a first-line treatment option. HNS therapy, however, should be considered as one alternative therapeutic option for patients meeting the inclusion criteria when more traditional therapeutic options have been considered.</abstract><cop>Tokyo</cop><pub>Springer Japan</pub><doi>10.1007/s41105-020-00252-2</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-7740-9013</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 1446-9235
ispartof Sleep and biological rhythms, 2020, Vol.18 (2), p.77-87
issn 1446-9235
1479-8425
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10686243
source SpringerLink Journals
subjects Biomedical and Life Sciences
Biomedicine
Health Psychology
Human Physiology
Internal Medicine
Neurology
Neurosciences
Psychiatry
Review Article
title Nerve stimulation for the treatment of obstructive sleep apnea
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T09%3A04%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Nerve%20stimulation%20for%20the%20treatment%20of%20obstructive%20sleep%20apnea&rft.jtitle=Sleep%20and%20biological%20rhythms&rft.au=Yamauchi,%20Motoo&rft.date=2020&rft.volume=18&rft.issue=2&rft.spage=77&rft.epage=87&rft.pages=77-87&rft.issn=1446-9235&rft.eissn=1479-8425&rft_id=info:doi/10.1007/s41105-020-00252-2&rft_dat=%3Cproquest_pubme%3E2895711008%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2895711008&rft_id=info:pmid/&rfr_iscdi=true