1,5-anhydro-D-fructose induces anti-aging effects on aging-associated brain diseases by increasing 5’-adenosine monophosphate-activated protein kinase activity via the peroxisome proliferator-activated receptor-γ co-activator-1α/brain-derived neurotrophic factor pathway

5'-Adenosine monophosphate-activated protein kinase (AMPK) is a metabolic sensor that serves as a cellular housekeeper; it also controls energy homeostasis and stress resistance. Thus, correct regulation of this factor can enhance health and survival. AMPK signaling may have a critical role in...

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Veröffentlicht in:Aging (Albany, NY.) NY.), 2023-11, Vol.15 (21), p.11740-11763, Article 11740-11763
Hauptverfasser: Kikuchi, Kiyoshi, Otsuka, Shotaro, Takada, Seiya, Nakanishi, Kazuki, Setoyama, Kentaro, Sakakima, Harutoshi, Tanaka, Eiichiro, Maruyama, Ikuro
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Sprache:eng
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