Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis

The architecture of individual cells and cell collectives enables functional specification, a prominent example being the formation of epithelial tubes that transport fluid or gas in many organs. The intrahepatic bile ducts (IHBDs) form a tubular network within the liver parenchyma that transports b...

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Veröffentlicht in:	Development (Cambridge) 2018-05, Vol.145 (9), p.dev162123-dev162123
Hauptverfasser:	Benhamouche-Trouillet, Samira, O'Loughlin, Evan, Liu, Ching-Hui, Polacheck, William, Fitamant, Julien, McKee, Mary, El-Bardeesy, Nabeel, Chen, Christopher S, McClatchey, Andrea I
Format:	Artikel
Sprache:	eng
Schlagworte:	Bile Bile ducts Intestine Liver Morphogenesis Neurofibromatosis Neurofibromatosis 2 Neurofibromin 1 Neurofibromin 2 Parenchyma Phenotypes Tumor suppressor genes Tumorigenesis
Online-Zugang:	Volltext
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