The catecholaldehyde hypothesis: where MAO fits in

Monoamine oxidase (MAO) plays a central role in the metabolism of the neurotransmitters dopamine, norepinephrine, and serotonin. This brief review focuses on 3,4-dihydroxyphenylacetaldehyde (DOPAL), which is the immediate product of MAO acting on cytoplasmic dopamine. DOPAL is toxic; however, normal...

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Veröffentlicht in:	Journal of Neural Transmission 2020-02, Vol.127 (2), p.169-177
1. Verfasser:	Goldstein, David S.
Format:	Artikel
Sprache:	eng
Schlagworte:	3,4-Dihydroxyphenylacetic Acid - analogs & derivatives 3,4-Dihydroxyphenylacetic Acid - metabolism Aldehyde Dehydrogenase - metabolism Animals Dopamine - metabolism Humans Medicine Medicine & Public Health Monoamine Oxidase - metabolism Neurodegenerative Diseases - metabolism Neurology Neurology and Preclinical Neurological Studies - Review Article Neurons - metabolism Neurosciences Psychiatry
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