Hydroxytyrosol produced by engineered Escherichia coli strains activates Nrf2/HO-1 pathway: An in vitro and in vivo study

This study explores the biological effects of hydroxytyrosol (HT), produced by the metabolic engineering of Escherichia coli, in a series of in vitro and in vivo experiments. In particular, a metabolically engineered Escherichia coli strain capable of producing HT was constructed and utilized. HEK29...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2023-09, Vol.248 (18), p.1598-1612
Hauptverfasser:	Simos, Yannis V, Zerikiotis, Stelios, Lekkas, Panagiotis, Zachariou, Christianna, Halabalaki, Maria, Ververidis, Filippos, Trantas, Emmanouil A, Tsamis, Konstantinos, Peschos, Dimitrios, Angelidis, Charalampos, Vezyraki, Patra
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - metabolism HEK293 Cells HeLa Cells Humans Male Mice NF-E2-Related Factor 2 - genetics NF-E2-Related Factor 2 - metabolism Original Research Oxidative Stress
Online-Zugang:	Volltext
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