Langerhans Cell Histiocytosis of the Nose and Maxilla: A Rare Presentation
Langerhans cell histiocytosis (LCH) is a disease characterized by localized and generalized proliferation of the histiocytes. It is a locally aggressive condition. The clinical presentation is highly variable and can range from isolated, self-healing skin or bone lesions to life-threatening multisys...
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| Veröffentlicht in: | Indian journal of otolaryngology, and head, and neck surgery and head, and neck surgery, 2023-12, Vol.75 (4), p.4106-4109 |
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| container_title | Indian journal of otolaryngology, and head, and neck surgery |
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| creator | Sekar, Raghul Raja, Kalaiarasi |
| description | Langerhans cell histiocytosis (LCH) is a disease characterized by localized and generalized proliferation of the histiocytes. It is a locally aggressive condition. The clinical presentation is highly variable and can range from isolated, self-healing skin or bone lesions to life-threatening multisystem disease. It can present as a unifocal or multifocal disease. The majority are present in the head and neck region, but the involvement of Paranasal sinuses is rare. Here we describe a 64-years-old female who presented with a slow-growing left nasal mass for 1 year. Evaluation of the patient was suggestive of malignancy, but the biopsy report turned out to be Langerhans cell histiocytosis; subsequently left, total maxillectomy was done. We hereby present a unique case of LCH with isolated nose and paranasal sinus involvement. |
| doi_str_mv | 10.1007/s12070-023-04075-8 |
| format | Article |
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It is a locally aggressive condition. The clinical presentation is highly variable and can range from isolated, self-healing skin or bone lesions to life-threatening multisystem disease. It can present as a unifocal or multifocal disease. The majority are present in the head and neck region, but the involvement of Paranasal sinuses is rare. Here we describe a 64-years-old female who presented with a slow-growing left nasal mass for 1 year. Evaluation of the patient was suggestive of malignancy, but the biopsy report turned out to be Langerhans cell histiocytosis; subsequently left, total maxillectomy was done. We hereby present a unique case of LCH with isolated nose and paranasal sinus involvement.</description><subject>Autoimmune diseases</subject><subject>Case reports</subject><subject>Clinical Report</subject><subject>Head and Neck Surgery</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Nose</subject><subject>Otorhinolaryngology</subject><subject>Sinuses</subject><issn>2231-3796</issn><issn>0973-7707</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9kUtPAyEUhYnRaK3-AReGxI2b0QvMDODGNI1aTX3E6JowDGPHTAeFqdF_L7VaHwtXJNzvnMvhILRD4IAA8MNAKHBIgLIEUuBZIlZQDyRnCefAV1GPUkYSxmW-gTZDeARgGeGwjjbiHU8Foz10Mdbtg_UT3QY8tE2DR3XoamfeOhfqgF2Fu4nFVy5YrNsSX-rXumn0ER7gW-0tvvE22LbTUdJuobVKN8Fuf559dH96cjccJePrs_PhYJwYJmiXCCmhkKywvIAsk7zMBDCg0tAChGAg0soCrwpeMZCS5NRowWRpShN1uS1ZHx0vfJ9mxdSWJu73ulFPvp5q_6acrtXvSVtP1IN7UQTyNIdURof9Twfvnmc2dGpaBxPT69a6WVBUSMKzyJKI7v1BH93MtzHfnAJIBYn_30d0QRnvQvC2Wr6GgJp3pRZdqciqj66UiKLdnzmWkq9yIsAWQIijeUvfu_-xfQdfNJ4Z</recordid><startdate>20231201</startdate><enddate>20231201</enddate><creator>Sekar, Raghul</creator><creator>Raja, Kalaiarasi</creator><general>Springer India</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-9514-6189</orcidid></search><sort><creationdate>20231201</creationdate><title>Langerhans Cell Histiocytosis of the Nose and Maxilla: A Rare Presentation</title><author>Sekar, Raghul ; Raja, Kalaiarasi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c382t-8990b93be7b05597d5803029c2b0883084fe07fb7f3099162ca839dcdc90b6ed3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Autoimmune diseases</topic><topic>Case reports</topic><topic>Clinical Report</topic><topic>Head and Neck Surgery</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Nose</topic><topic>Otorhinolaryngology</topic><topic>Sinuses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sekar, Raghul</creatorcontrib><creatorcontrib>Raja, Kalaiarasi</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Indian journal of otolaryngology, and head, and neck surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sekar, Raghul</au><au>Raja, Kalaiarasi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Langerhans Cell Histiocytosis of the Nose and Maxilla: A Rare Presentation</atitle><jtitle>Indian journal of otolaryngology, and head, and neck surgery</jtitle><stitle>Indian J Otolaryngol Head Neck Surg</stitle><addtitle>Indian J Otolaryngol Head Neck Surg</addtitle><date>2023-12-01</date><risdate>2023</risdate><volume>75</volume><issue>4</issue><spage>4106</spage><epage>4109</epage><pages>4106-4109</pages><issn>2231-3796</issn><eissn>0973-7707</eissn><abstract>Langerhans cell histiocytosis (LCH) is a disease characterized by localized and generalized proliferation of the histiocytes. It is a locally aggressive condition. The clinical presentation is highly variable and can range from isolated, self-healing skin or bone lesions to life-threatening multisystem disease. It can present as a unifocal or multifocal disease. The majority are present in the head and neck region, but the involvement of Paranasal sinuses is rare. Here we describe a 64-years-old female who presented with a slow-growing left nasal mass for 1 year. Evaluation of the patient was suggestive of malignancy, but the biopsy report turned out to be Langerhans cell histiocytosis; subsequently left, total maxillectomy was done. We hereby present a unique case of LCH with isolated nose and paranasal sinus involvement.</abstract><cop>New Delhi</cop><pub>Springer India</pub><pmid>37974832</pmid><doi>10.1007/s12070-023-04075-8</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0002-9514-6189</orcidid></addata></record> |
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| source | Springer Nature - Complete Springer Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Autoimmune diseases Case reports Clinical Report Head and Neck Surgery Medicine Medicine & Public Health Nose Otorhinolaryngology Sinuses |
| title | Langerhans Cell Histiocytosis of the Nose and Maxilla: A Rare Presentation |
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