Blazing a trail for the clinical use of rapamycin as a geroprotecTOR

Treatment with rapamycin, an inhibitor of the mechanistic Target Of Rapamycin Complex One (mTORC1) protein kinase, has been repeatedly demonstrated to extend lifespan and prevent or delay age-related diseases in diverse model systems. Concerns over the risk of potentially serious side effects in hum...

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Veröffentlicht in:GeroScience 2023-10, Vol.45 (5), p.2769-2783
Hauptverfasser: Konopka, Adam R., Lamming, Dudley W.
Format: Artikel
Sprache:eng
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