EXTH-64. ESTABLISHING A CLINICALLY RELEVANT MOUSE MODEL OF MESENCHYMAL GLIOBLASTOMA FOR STUDYING TME TARGETING TREATMENTS

Abstract Historically, pre-clinical GBM models have largely failed to predict response in the clinical setting. Here, we establish a more clinically faithful model using the syngeneic NFpp10a-Luc2 mesenchymal-GBM cell line to study response to resection and temozolomide (TMZ), adjuvant/neo-adjuvant...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2023-11, Vol.25 (Supplement_5), p.v238-v239
Hauptverfasser:	Connor, Kate, White, Kieron, Clerkin, James, Shiels, Liam, Sweeney, Kieron, Van Brussel, Thomas, Arijs, Ingrid, Lambrechts, Diether, Shankar, Gautam, de Smet, Frederik, Zopf, Dieter, Maher, Stephen, Marignol, Laure, Dicker, Patrick, Prehn, Jochen, O'Brien, David, Byrne, Annette
Format:	Artikel
Sprache:	eng
Schlagworte:	Preclinical Experimental Therapeutics
Online-Zugang:	Volltext
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