DDDR-05. TARGETED INHIBITION OF DNA REPAIR AND SURVIVAL SIGNALING IN DIFFUSE INTRINSIC PONTINE GLIOMAS

Abstract Therapeutic resistance remains a major obstacle to successful clinical management of Diffuse Intrinsic Pontine Glioma (DIPG), a high-grade pediatric tumor of the brain stem. In nearly all patients, available therapies fail to prevent progression. Innovative combinatorial therapies that pene...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2023-11, Vol.25 (Supplement_5), p.v105-v106
Hauptverfasser:	Barravecchia, Ivana, Sharma, Monika, Teis, Robert, Cruz, Jeanette, Mumby, Rachel, Ziemke, Elizabeth, Espinoza, Carlos, Krishnamoorthy, Varunkumar, Magnuson, Brian, Ljungman, Mats, Koschmann, Carl, Whitehead, Christopher, Sebolt-Leopold, Judith, Galban, Stefanie
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug Discovery, Drug Resistance
Online-Zugang:	Volltext
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