Sustained Pituitary T3 Production Explains the T4-mediated TSH Feedback Mechanism

Abstract The regulation of thyroid activity and thyroid hormone (TH) secretion is based on feedback mechanisms that involve the anterior pituitary TSH and medial basal hypothalamus TSH-releasing hormone. Plasma T3 levels can be “sensed” directly by the anterior pituitary and medial basal hypothalamu...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2023-11, Vol.164 (12), p.1
Hauptverfasser:	Batistuzzo, Alice, Salas-Lucia, Federico, Gereben, Balázs, Ribeiro, Miriam O, Bianco, Antonio C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone marrow Explants Feedback Humans Hypothalamus Hypothalamus (anterior) Hypothalamus (medial) Iodide peroxidase Iodine Radioisotopes Kidneys Mice Muscles Physiological aspects Pituitary (anterior) Pituitary gland Pituitary Gland - metabolism Pituitary hormones Skeletal muscle Swine Thyroid Thyroid gland Thyroid-stimulating hormone Thyrotropin Thyroxine Thyroxine - metabolism Triiodothyronine Triiodothyronine - metabolism
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