Cancer Cell Membrane Wrapped Nanoparticles for the Delivery of a Bcl‑2 Inhibitor to Triple-Negative Breast Cancer

Overexpression of the antiapoptotic protein B-cell lymphoma 2 (Bcl-2) is correlated with poor survival outcomes in triple-negative breast cancer (TNBC), making Bcl-2 inhibition a promising strategy to treat this aggressive disease. Unfortunately, Bcl-2 inhibitors developed to date have limited clini...

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Veröffentlicht in:	Molecular pharmaceutics 2023-08, Vol.20 (8), p.3895-3913
Hauptverfasser:	Scully, Mackenzie A., Wilkins, Dana E., Dang, Megan N., Hoover, Elise C., Aboeleneen, Sara B., Day, Emily S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Cell Line, Tumor Cell Membrane Humans Mice Nanoparticles Triple Negative Breast Neoplasms - drug therapy
Online-Zugang:	Volltext
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