Modelling DTPA therapy following Am contamination in rats

A major challenge in modelling the decorporation of actinides (An), such as americium (Am), with DTPA (diethylenetriaminepentaacetic acid) is the fact that standard biokinetic models become inadequate for assessing radionuclide intake and estimating the resulting dose, as DTPA perturbs the regular b...

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Veröffentlicht in:	Radiation and environmental biophysics 2023-11, Vol.62 (4), p.483-495
Hauptverfasser:	Kastl, Manuel, Grémy, Olivier, Lamart, Stephanie, Giussani, Augusto, Li, Wei Bo, Hoeschen, Christoph
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinides Americium Biological and Medical Physics Biophysics Chelates Chelating agents Chelation Contamination Diethylenetriamine pentaacetic acid Ecosystems Effects of Radiation/Radiation Protection Environmental Physics Excretion Hepatocytes Life Sciences Liver Modelling Monitoring/Environmental Analysis Physics Physics and Astronomy Plutonium Radiation Radioisotopes Retention Toxicology
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