Disrupted stiffness ratio alters nuclear mechanosensing

The ability of endothelial cells to sense and respond to dynamic changes in blood flow is critical for vascular homeostasis and cardiovascular health. The mechanical and geometric properties of the nuclear and cytoplasmic compartments affect mechanotransduction. We hypothesized that alterations of t...

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Veröffentlicht in:	Matter 2023-10, Vol.6 (10), p.3608-3630
Hauptverfasser:	Walther, Brandon K., Sears, Adam P., Mojiri, Anahita, Avazmohammadi, Reza, Gu, Jianhua, Chumakova, Olga V., Rajeeva Pandian, Navaneeth Krishna, Dominic, Abishai, Martiel, Jean-Louis, Yazdani, Saami K., Cooke, John P., Ohayon, Jacques, Pettigrew, Roderic I.
Format:	Artikel
Sprache:	eng
Schlagworte:	biomechanics biophysics Cognitive science endothelial cells Life Sciences mechanobiology Neuroscience shear stress soft matter
Online-Zugang:	Volltext
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