Scorpion venom heat-resistant peptide alleviates mitochondrial dynamics imbalance induced by PM2.5 exposure by downregulating the PGC-1α/SIRT3 signaling pathway

Abstract Background Epidemiological inquiry reveals that neuroinflammation and mitochondrial dysfunction caused by PM2.5 exposure are associated with Alzheimer’s disease. Nevertheless, the molecular mechanisms of mitochondrial dynamics and neuroinflammation induced by PM2.5 exposure remain elusive....

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Veröffentlicht in:Toxicology research (Cambridge) 2023-10, Vol.12 (5), p.756-764
Hauptverfasser: Huang, Lanyi, Xu, Jingbin, Duan, Kaiqian, Bao, Tuya, Cheng, Yu, Zhang, Haimin, Zhang, Yong, Lin, Yingwei, Li, Fasheng
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Sprache:eng
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