Psychotropic Medication Adherence and Its Associated Factors Among Schizophrenia Patients: Exploring the Consistency of Adherence Scales
Background and objectiveNon-adherence to psychotropic medication can aggravate an individual's illness, diminish treatment efficacy, or make patients less responsive to future therapeutic interventions. There are several scales available to measure non-adherence to medications. In this study, w...
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creator | Ali, Maghzoub M Taha, Manal M Ahmed, Anas E Ali, Suhaila Baiti, Maisa A Alhazmi, Atyaf A Alfaifi, Bushra A Majrabi, Rania Q Khormi, Nidaa Q Hakami, Alyaj A Alqaari, Rafa A Alhasani, Raffan A Abdelwahab, Siddig I |
description | Background and objectiveNon-adherence to psychotropic medication can aggravate an individual's illness, diminish treatment efficacy, or make patients less responsive to future therapeutic interventions. There are several scales available to measure non-adherence to medications. In this study, we aimed to measure psychotropic medication adherence and its associated factors among schizophrenic outpatients in Saudi Arabia.MethodologyA cross-sectional study was conducted with a view to measuring psychotropic medication adherence and its associated factors. The Medication Adherence Rating Scale (MARS) and the Drug Attitude Inventory-10 (DAI-10) were translated into Arabic, and their internal consistency was measured. The adjusted odds ratios (AOR) were calculated using logistic regression in the IBM SPSS Statistics software version 23 (IBM Corp., Armonk, NY).ResultsSpearman's rho correlation indicated a negative association between DAI-10 and MARS scores (r = -0.579; p |
doi_str_mv | 10.7759/cureus.46118 |
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fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10612138</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2884557137</sourcerecordid><originalsourceid>FETCH-LOGICAL-c320t-454a07edbeaca8d22c3c432ba0482abc500ee5243dacb665829c81520344b9593</originalsourceid><addsrcrecordid>eNpdkV1LHDEUhodSoaLe9QcEvOlFV_M5k-1NWRa_QKmgvQ6ZM2edyGwyTTKl6y_wZxtdEe3VCSdPHt7wVtVXRo-aRs2PYYo4pSNZM6Y_Vbuc1XqmmZaf352_VAcp3VNKGW04behu9XidNtCHHMPogFxh58BmFzxZdD1G9IDE-o5c5EQWKQVwNmNHTi3kEMtqHfwduYHePYSxL7iz5Lq8R5_TD3LybxxCdIXIPZJl8MmlXJQbElbv_DdgB0z71c7KDgkPXude9fv05HZ5Prv8dXaxXFzOQHCaZ1JJSxvsWrRgdcc5CJCCt5ZKzW0LilJExaXoLLR1rTSfg2aKUyFlO1dzsVf93HrHqV1jByVqtIMZo1vbuDHBOvPxxrve3IW_htGacSZ0MXx7NcTwZ8KUzdolwGGwHsOUDNdaMl1wWtDD_9D7MEVf_vdCKdUw0RTq-5aCGFKKuHpLw6h57tZsuzUv3YonC8ybSw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2884557137</pqid></control><display><type>article</type><title>Psychotropic Medication Adherence and Its Associated Factors Among Schizophrenia Patients: Exploring the Consistency of Adherence Scales</title><source>PubMed Central</source><source>PubMed Central Open Access</source><creator>Ali, Maghzoub M ; Taha, Manal M ; Ahmed, Anas E ; Ali, Suhaila ; Baiti, Maisa A ; Alhazmi, Atyaf A ; Alfaifi, Bushra A ; Majrabi, Rania Q ; Khormi, Nidaa Q ; Hakami, Alyaj A ; Alqaari, Rafa A ; Alhasani, Raffan A ; Abdelwahab, Siddig I</creator><creatorcontrib>Ali, Maghzoub M ; Taha, Manal M ; Ahmed, Anas E ; Ali, Suhaila ; Baiti, Maisa A ; Alhazmi, Atyaf A ; Alfaifi, Bushra A ; Majrabi, Rania Q ; Khormi, Nidaa Q ; Hakami, Alyaj A ; Alqaari, Rafa A ; Alhasani, Raffan A ; Abdelwahab, Siddig I</creatorcontrib><description>Background and objectiveNon-adherence to psychotropic medication can aggravate an individual's illness, diminish treatment efficacy, or make patients less responsive to future therapeutic interventions. There are several scales available to measure non-adherence to medications. In this study, we aimed to measure psychotropic medication adherence and its associated factors among schizophrenic outpatients in Saudi Arabia.MethodologyA cross-sectional study was conducted with a view to measuring psychotropic medication adherence and its associated factors. The Medication Adherence Rating Scale (MARS) and the Drug Attitude Inventory-10 (DAI-10) were translated into Arabic, and their internal consistency was measured. The adjusted odds ratios (AOR) were calculated using logistic regression in the IBM SPSS Statistics software version 23 (IBM Corp., Armonk, NY).ResultsSpearman's rho correlation indicated a negative association between DAI-10 and MARS scores (r = -0.579; p<0.05). The Arabic version of MARS was more reliable than DAI-10, as evidenced by Cronbach's alpha value. Of note, 60.20% (n = 59) of the sample demonstrated high adherence levels. The adherence level based on MARS scoring remained unaffected (p>0.05) in terms of gender, age, employment, marital status, educational level, income level, and duration of sickness. These results were obtained by using the multivariate logistic regression model; 89% of respondents reported not using psychiatric drugs given by someone else, despite the adherence rate not affecting this number.ConclusionThe rate of non-adherence to psychotropic treatment was found to be high in our cohort. Hence, it is imperative to develop comprehensive intervention methods targeting the causes of non-adherence to psychiatric medication.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.46118</identifier><language>eng</language><publisher>Palo Alto: Cureus Inc</publisher><subject>Consent ; Data analysis ; Data collection ; Drug abuse ; Mental disorders ; Outpatient care facilities ; Patient compliance ; Pilot projects ; Psychiatry ; Psychology ; Psychotropic drugs ; Public Health ; Questionnaires ; Regression analysis ; Schizophrenia ; Validation studies ; Validity</subject><ispartof>Curēus (Palo Alto, CA), 2023-09, Vol.15 (9), p.e46118-e46118</ispartof><rights>Copyright © 2023, Ali et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2023, Ali et al. 2023 Ali et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c320t-454a07edbeaca8d22c3c432ba0482abc500ee5243dacb665829c81520344b9593</citedby><cites>FETCH-LOGICAL-c320t-454a07edbeaca8d22c3c432ba0482abc500ee5243dacb665829c81520344b9593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612138/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612138/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids></links><search><creatorcontrib>Ali, Maghzoub M</creatorcontrib><creatorcontrib>Taha, Manal M</creatorcontrib><creatorcontrib>Ahmed, Anas E</creatorcontrib><creatorcontrib>Ali, Suhaila</creatorcontrib><creatorcontrib>Baiti, Maisa A</creatorcontrib><creatorcontrib>Alhazmi, Atyaf A</creatorcontrib><creatorcontrib>Alfaifi, Bushra A</creatorcontrib><creatorcontrib>Majrabi, Rania Q</creatorcontrib><creatorcontrib>Khormi, Nidaa Q</creatorcontrib><creatorcontrib>Hakami, Alyaj A</creatorcontrib><creatorcontrib>Alqaari, Rafa A</creatorcontrib><creatorcontrib>Alhasani, Raffan A</creatorcontrib><creatorcontrib>Abdelwahab, Siddig I</creatorcontrib><title>Psychotropic Medication Adherence and Its Associated Factors Among Schizophrenia Patients: Exploring the Consistency of Adherence Scales</title><title>Curēus (Palo Alto, CA)</title><description>Background and objectiveNon-adherence to psychotropic medication can aggravate an individual's illness, diminish treatment efficacy, or make patients less responsive to future therapeutic interventions. There are several scales available to measure non-adherence to medications. In this study, we aimed to measure psychotropic medication adherence and its associated factors among schizophrenic outpatients in Saudi Arabia.MethodologyA cross-sectional study was conducted with a view to measuring psychotropic medication adherence and its associated factors. The Medication Adherence Rating Scale (MARS) and the Drug Attitude Inventory-10 (DAI-10) were translated into Arabic, and their internal consistency was measured. The adjusted odds ratios (AOR) were calculated using logistic regression in the IBM SPSS Statistics software version 23 (IBM Corp., Armonk, NY).ResultsSpearman's rho correlation indicated a negative association between DAI-10 and MARS scores (r = -0.579; p<0.05). The Arabic version of MARS was more reliable than DAI-10, as evidenced by Cronbach's alpha value. Of note, 60.20% (n = 59) of the sample demonstrated high adherence levels. The adherence level based on MARS scoring remained unaffected (p>0.05) in terms of gender, age, employment, marital status, educational level, income level, and duration of sickness. These results were obtained by using the multivariate logistic regression model; 89% of respondents reported not using psychiatric drugs given by someone else, despite the adherence rate not affecting this number.ConclusionThe rate of non-adherence to psychotropic treatment was found to be high in our cohort. Hence, it is imperative to develop comprehensive intervention methods targeting the causes of non-adherence to psychiatric medication.</description><subject>Consent</subject><subject>Data analysis</subject><subject>Data collection</subject><subject>Drug abuse</subject><subject>Mental disorders</subject><subject>Outpatient care facilities</subject><subject>Patient compliance</subject><subject>Pilot projects</subject><subject>Psychiatry</subject><subject>Psychology</subject><subject>Psychotropic drugs</subject><subject>Public Health</subject><subject>Questionnaires</subject><subject>Regression analysis</subject><subject>Schizophrenia</subject><subject>Validation studies</subject><subject>Validity</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdkV1LHDEUhodSoaLe9QcEvOlFV_M5k-1NWRa_QKmgvQ6ZM2edyGwyTTKl6y_wZxtdEe3VCSdPHt7wVtVXRo-aRs2PYYo4pSNZM6Y_Vbuc1XqmmZaf352_VAcp3VNKGW04behu9XidNtCHHMPogFxh58BmFzxZdD1G9IDE-o5c5EQWKQVwNmNHTi3kEMtqHfwduYHePYSxL7iz5Lq8R5_TD3LybxxCdIXIPZJl8MmlXJQbElbv_DdgB0z71c7KDgkPXude9fv05HZ5Prv8dXaxXFzOQHCaZ1JJSxvsWrRgdcc5CJCCt5ZKzW0LilJExaXoLLR1rTSfg2aKUyFlO1dzsVf93HrHqV1jByVqtIMZo1vbuDHBOvPxxrve3IW_htGacSZ0MXx7NcTwZ8KUzdolwGGwHsOUDNdaMl1wWtDD_9D7MEVf_vdCKdUw0RTq-5aCGFKKuHpLw6h57tZsuzUv3YonC8ybSw</recordid><startdate>20230928</startdate><enddate>20230928</enddate><creator>Ali, Maghzoub M</creator><creator>Taha, Manal M</creator><creator>Ahmed, Anas E</creator><creator>Ali, Suhaila</creator><creator>Baiti, Maisa A</creator><creator>Alhazmi, Atyaf A</creator><creator>Alfaifi, Bushra A</creator><creator>Majrabi, Rania Q</creator><creator>Khormi, Nidaa Q</creator><creator>Hakami, Alyaj A</creator><creator>Alqaari, Rafa A</creator><creator>Alhasani, Raffan A</creator><creator>Abdelwahab, Siddig I</creator><general>Cureus Inc</general><general>Cureus</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20230928</creationdate><title>Psychotropic Medication Adherence and Its Associated Factors Among Schizophrenia Patients: Exploring the Consistency of Adherence Scales</title><author>Ali, Maghzoub M ; Taha, Manal M ; Ahmed, Anas E ; Ali, Suhaila ; Baiti, Maisa A ; Alhazmi, Atyaf A ; Alfaifi, Bushra A ; Majrabi, Rania Q ; Khormi, Nidaa Q ; Hakami, Alyaj A ; Alqaari, Rafa A ; Alhasani, Raffan A ; Abdelwahab, Siddig I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c320t-454a07edbeaca8d22c3c432ba0482abc500ee5243dacb665829c81520344b9593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Consent</topic><topic>Data analysis</topic><topic>Data collection</topic><topic>Drug abuse</topic><topic>Mental disorders</topic><topic>Outpatient care facilities</topic><topic>Patient compliance</topic><topic>Pilot projects</topic><topic>Psychiatry</topic><topic>Psychology</topic><topic>Psychotropic drugs</topic><topic>Public Health</topic><topic>Questionnaires</topic><topic>Regression analysis</topic><topic>Schizophrenia</topic><topic>Validation studies</topic><topic>Validity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ali, Maghzoub M</creatorcontrib><creatorcontrib>Taha, Manal M</creatorcontrib><creatorcontrib>Ahmed, Anas E</creatorcontrib><creatorcontrib>Ali, Suhaila</creatorcontrib><creatorcontrib>Baiti, Maisa A</creatorcontrib><creatorcontrib>Alhazmi, Atyaf A</creatorcontrib><creatorcontrib>Alfaifi, Bushra A</creatorcontrib><creatorcontrib>Majrabi, Rania Q</creatorcontrib><creatorcontrib>Khormi, Nidaa Q</creatorcontrib><creatorcontrib>Hakami, Alyaj A</creatorcontrib><creatorcontrib>Alqaari, Rafa A</creatorcontrib><creatorcontrib>Alhasani, Raffan A</creatorcontrib><creatorcontrib>Abdelwahab, Siddig I</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ali, Maghzoub M</au><au>Taha, Manal M</au><au>Ahmed, Anas E</au><au>Ali, Suhaila</au><au>Baiti, Maisa A</au><au>Alhazmi, Atyaf A</au><au>Alfaifi, Bushra A</au><au>Majrabi, Rania Q</au><au>Khormi, Nidaa Q</au><au>Hakami, Alyaj A</au><au>Alqaari, Rafa A</au><au>Alhasani, Raffan A</au><au>Abdelwahab, Siddig I</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Psychotropic Medication Adherence and Its Associated Factors Among Schizophrenia Patients: Exploring the Consistency of Adherence Scales</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><date>2023-09-28</date><risdate>2023</risdate><volume>15</volume><issue>9</issue><spage>e46118</spage><epage>e46118</epage><pages>e46118-e46118</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Background and objectiveNon-adherence to psychotropic medication can aggravate an individual's illness, diminish treatment efficacy, or make patients less responsive to future therapeutic interventions. There are several scales available to measure non-adherence to medications. In this study, we aimed to measure psychotropic medication adherence and its associated factors among schizophrenic outpatients in Saudi Arabia.MethodologyA cross-sectional study was conducted with a view to measuring psychotropic medication adherence and its associated factors. The Medication Adherence Rating Scale (MARS) and the Drug Attitude Inventory-10 (DAI-10) were translated into Arabic, and their internal consistency was measured. The adjusted odds ratios (AOR) were calculated using logistic regression in the IBM SPSS Statistics software version 23 (IBM Corp., Armonk, NY).ResultsSpearman's rho correlation indicated a negative association between DAI-10 and MARS scores (r = -0.579; p<0.05). The Arabic version of MARS was more reliable than DAI-10, as evidenced by Cronbach's alpha value. Of note, 60.20% (n = 59) of the sample demonstrated high adherence levels. The adherence level based on MARS scoring remained unaffected (p>0.05) in terms of gender, age, employment, marital status, educational level, income level, and duration of sickness. These results were obtained by using the multivariate logistic regression model; 89% of respondents reported not using psychiatric drugs given by someone else, despite the adherence rate not affecting this number.ConclusionThe rate of non-adherence to psychotropic treatment was found to be high in our cohort. Hence, it is imperative to develop comprehensive intervention methods targeting the causes of non-adherence to psychiatric medication.</abstract><cop>Palo Alto</cop><pub>Cureus Inc</pub><doi>10.7759/cureus.46118</doi><oa>free_for_read</oa></addata></record> |
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subjects | Consent Data analysis Data collection Drug abuse Mental disorders Outpatient care facilities Patient compliance Pilot projects Psychiatry Psychology Psychotropic drugs Public Health Questionnaires Regression analysis Schizophrenia Validation studies Validity |
title | Psychotropic Medication Adherence and Its Associated Factors Among Schizophrenia Patients: Exploring the Consistency of Adherence Scales |
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