Customized Loading of microRNA-126 to Small Extracellular Vesicle-Derived Vehicles Improves Cardiac Function after Myocardial Infarction

Small extracellular vesicles (sEVs) are promising for cell-based cardiac repair after myocardial infarction. These sEVs encapsulate potent cargo, including microRNAs (miRs), within a bilayer membrane that aids sEV uptake when administered to cells. However, despite their efficacy, sEV therapies are...

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Veröffentlicht in:	ACS nano 2023-10, Vol.17 (20), p.19613-19624
Hauptverfasser:	Bheri, Sruti, Brown, Milton E., Park, Hyun-Ji, Brazhkina, Olga, Takaesu, Felipe, Davis, Michael E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Endothelial Cells Extracellular Vesicles Ischemia MicroRNAs - genetics Myocardial Infarction - therapy Rats
Online-Zugang:	Volltext
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