Extending the reach of homology by using successive computational filters to find yeast pheromone genes

The mating of fungi depends on pheromones that mediate communication between two mating types. Most species use short peptides as pheromones, which are either unmodified (e.g., α-factor in Saccharomyces cerevisiae) or C-terminally farnesylated (e.g., a-factor in S. cerevisiae). Peptide pheromones ha...

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Veröffentlicht in:	Current biology 2023-10, Vol.33 (19), p.4098-4110.e3
Hauptverfasser:	Srikant, Sriram, Gaudet, Rachelle, Murray, Andrew W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ascomycota - metabolism gene annotation Genes, Fungal Mating Factor - genetics Mating Factor - metabolism Peptides - metabolism pheromones Pheromones - metabolism Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism small peptides Yarrowia yeast mating
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