Targeting innate immune pathways for cancer immunotherapy

The innate immune system is critical for inducing durable and protective T cell responses to infection and has been increasingly recognized as a target for cancer immunotherapy. In this review, we present a framework wherein distinct innate immune signaling pathways activate five key dendritic cell...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2023-10, Vol.56 (10), p.2206-2217
Hauptverfasser:	Cao, Longyue L., Kagan, Jonathan C.
Format:	Artikel
Sprache:	eng
Schlagworte:	anti-tumor immunity cancer vaccines cGAS Cytokines dendritic cells Humans IL-1 Immunity, Innate Immunotherapy inflammasomes innate immunity Neoplasms pattern recognition receptors Signal Transduction STING TLRs Toll-like receptors Tumor Microenvironment
Online-Zugang:	Volltext
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