Characterization of mutations in the rpoB gene that confer rifampin resistance in Staphylococcus aureus

Mutations in the rifampin resistance-determining (Rif) regions of the rpoB gene of Staphylococcus aureus mutants obtained during therapy or in vitro were analyzed by gene amplification and sequencing. Each of the resistant clinical isolates, including five nonrelated clones and two strains isolated...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 1998-10, Vol.42 (10), p.2590-2594
Hauptverfasser:	AUBRY-DAMON, H, SOUSSY, C.-J, COURVALIN, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antibacterial agents Antibiotics, Antitubercular - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences DNA-Directed RNA Polymerases Drug Resistance, Microbial Genes, Bacterial Humans Mechanisms of Resistance Medical sciences Molecular Sequence Data Mutation Pharmacology. Drug treatments Plant Proteins - genetics Rifampin - pharmacology Staphylococcus aureus Staphylococcus aureus - drug effects
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