Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway

Visible impairments in skin appearance, as well as a subtle decline in its functionality at the molecular level, are hallmarks of skin aging. Activation of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-pathway, which is important in controlling inflammation and oxidative stress that occur d...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2021-12, Vol.98, p.108817-108817, Article 108817
Hauptverfasser:	Petkovic, Marija, Leal, Ermelindo C, Alves, Ines, Bose, Chanda, Palade, Philip T, Singh, Preeti, Awasthi, Sanjay, Børsheim, Elisabet, Dalgaard, Louise T, Singh, Sharda P, Carvalho, Eugenia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Cruciferous vegetables Dietary Supplements Inflammation - drug therapy Inflammation - metabolism Isothiocyanates - pharmacology Kelch-Like ECH-Associated Protein 1 - metabolism Male Matrix Metalloproteinase 9 - metabolism Mice Mice, Inbred C57BL NF-E2-Related Factor 2 - metabolism Nrf2 pathway oxidative stress Oxidative Stress - drug effects Reactive Oxygen Species - metabolism skin aging Skin Aging - drug effects sulforaphane Sulfoxides - pharmacology
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