Neurosyphilis with oral‑facial‑lingual dyskinesia: A case report
. The present study describes the case of a 52-year-old male patient who presented with subacute onset dysarthria and oral-facial-lingual dyskinesia, with normal blood glucose and acanthocyte levels, and no history of drug use. The patient tested negative for autoimmune encephalitis-related antibodi...
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| Veröffentlicht in: | Experimental and therapeutic medicine 2023-11, Vol.26 (5), Article 520 |
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| creator | Liang, Yingfang Li, Bixun Ou, Danyan Li, Guoliang Zeng, Hao |
| description | . The present study describes the case of a 52-year-old male patient who presented with subacute onset dysarthria and oral-facial-lingual dyskinesia, with normal blood glucose and acanthocyte levels, and no history of drug use. The patient tested negative for autoimmune encephalitis-related antibodies and paraneoplastic-related antibodies. The level of cerebrospinal fluid (CSF) protein was slightly elevated, and the Treponema pallidum hemagglutination assay and rapid plasma reagin test were positive in both serum and CSF samples. After 1 month of treatment with doxycycline, the patient's oral-facial-lingual dyskinesia was significantly improved, suggesting the diagnosis of neurosyphilis. Key words: syphilis, dyskinesia, rhythmic orofacial involuntary movements, neurosyphilis, orofacial |
| doi_str_mv | 10.3892/etm.2023.12219 |
| format | Article |
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The present study describes the case of a 52-year-old male patient who presented with subacute onset dysarthria and oral-facial-lingual dyskinesia, with normal blood glucose and acanthocyte levels, and no history of drug use. The patient tested negative for autoimmune encephalitis-related antibodies and paraneoplastic-related antibodies. The level of cerebrospinal fluid (CSF) protein was slightly elevated, and the Treponema pallidum hemagglutination assay and rapid plasma reagin test were positive in both serum and CSF samples. After 1 month of treatment with doxycycline, the patient's oral-facial-lingual dyskinesia was significantly improved, suggesting the diagnosis of neurosyphilis. Key words: syphilis, dyskinesia, rhythmic orofacial involuntary movements, neurosyphilis, orofacial</description><identifier>ISSN: 1792-0981</identifier><identifier>EISSN: 1792-1015</identifier><identifier>DOI: 10.3892/etm.2023.12219</identifier><language>eng</language><publisher>Athens: Spandidos Publications</publisher><subject>Antibodies ; Autoimmune diseases ; Blood ; Brain diseases ; Case Report ; Case reports ; Causes of ; Complications and side effects ; Diagnosis ; Diagnostic tests ; Disease ; Drinking water ; Drug abuse ; Drug therapy ; Dysarthria ; Dyskinesia ; Encephalitis ; Hepatitis ; Ischemia ; Medical diagnosis ; Memory ; Mental disorders ; Movement disorders ; Nervous system ; Neurosyphilis ; Parkinson's disease ; Penicillin ; Proteins ; Substance abuse treatment ; Syphilis</subject><ispartof>Experimental and therapeutic medicine, 2023-11, Vol.26 (5), Article 520</ispartof><rights>COPYRIGHT 2023 Spandidos Publications</rights><rights>Copyright Spandidos Publications UK Ltd. 2023</rights><rights>Copyright: © Liang et al. 2023</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c315t-a453e8aafc7a732ee9e83390856d38972922a81b2ca8ac7944edabdb44c48cdc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580249/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580249/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27922,27923,53789,53791</link.rule.ids></links><search><creatorcontrib>Liang, Yingfang</creatorcontrib><creatorcontrib>Li, Bixun</creatorcontrib><creatorcontrib>Ou, Danyan</creatorcontrib><creatorcontrib>Li, Guoliang</creatorcontrib><creatorcontrib>Zeng, Hao</creatorcontrib><title>Neurosyphilis with oral‑facial‑lingual dyskinesia: A case report</title><title>Experimental and therapeutic medicine</title><description>. The present study describes the case of a 52-year-old male patient who presented with subacute onset dysarthria and oral-facial-lingual dyskinesia, with normal blood glucose and acanthocyte levels, and no history of drug use. The patient tested negative for autoimmune encephalitis-related antibodies and paraneoplastic-related antibodies. The level of cerebrospinal fluid (CSF) protein was slightly elevated, and the Treponema pallidum hemagglutination assay and rapid plasma reagin test were positive in both serum and CSF samples. After 1 month of treatment with doxycycline, the patient's oral-facial-lingual dyskinesia was significantly improved, suggesting the diagnosis of neurosyphilis. 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The present study describes the case of a 52-year-old male patient who presented with subacute onset dysarthria and oral-facial-lingual dyskinesia, with normal blood glucose and acanthocyte levels, and no history of drug use. The patient tested negative for autoimmune encephalitis-related antibodies and paraneoplastic-related antibodies. The level of cerebrospinal fluid (CSF) protein was slightly elevated, and the Treponema pallidum hemagglutination assay and rapid plasma reagin test were positive in both serum and CSF samples. After 1 month of treatment with doxycycline, the patient's oral-facial-lingual dyskinesia was significantly improved, suggesting the diagnosis of neurosyphilis. Key words: syphilis, dyskinesia, rhythmic orofacial involuntary movements, neurosyphilis, orofacial</abstract><cop>Athens</cop><pub>Spandidos Publications</pub><doi>10.3892/etm.2023.12219</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Antibodies Autoimmune diseases Blood Brain diseases Case Report Case reports Causes of Complications and side effects Diagnosis Diagnostic tests Disease Drinking water Drug abuse Drug therapy Dysarthria Dyskinesia Encephalitis Hepatitis Ischemia Medical diagnosis Memory Mental disorders Movement disorders Nervous system Neurosyphilis Parkinson's disease Penicillin Proteins Substance abuse treatment Syphilis |
| title | Neurosyphilis with oral‑facial‑lingual dyskinesia: A case report |
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