Effect of the SARS-CoV-2 Delta-associated G15U mutation on the s2m element dimerization and its interactions with miR-1307-3p

The s2m, a highly conserved 41-nt hairpin structure in the SARS-CoV-2 genome, serves as an attractive therapeutic target that may have important roles in the virus life cycle or interactions with the host. However, the conserved s2m in Delta SARS-CoV-2, a previously dominant variant characterized by...

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Veröffentlicht in:RNA (Cambridge) 2023-11, Vol.29 (11), p.1754-1771
Hauptverfasser: Cunningham, Caylee L, Frye, Caleb J, Makowski, Joseph A, Kensinger, Adam H, Shine, Morgan, Milback, Ella J, Lackey, Patrick E, Evanseck, Jeffrey D, Mihailescu, Mihaela-Rita
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Sprache:eng
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