Diagnostic challenges of incidental lung lesions on liver MRI during the COVID-19 pandemic

The CT uncovered multiple ground glass opacities in a bilateral, multilobar and peripheral distribution, corresponding to the British Society of Thoracic Imaging classification of, classic/probable COVID-19 infection.3 Figure 2 shows the CT. The lack of sensitivity of RT-PCR and the poor specificity...

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Veröffentlicht in:BMJ case reports 2020-07, Vol.13 (7), p.e237430
Hauptverfasser: Deen, Surrin Shazam, Wetscherek, Maria, Karia, Sumit, Godfrey, Edmund M
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Wetscherek, Maria
Karia, Sumit
Godfrey, Edmund M
description The CT uncovered multiple ground glass opacities in a bilateral, multilobar and peripheral distribution, corresponding to the British Society of Thoracic Imaging classification of, classic/probable COVID-19 infection.3 Figure 2 shows the CT. The lack of sensitivity of RT-PCR and the poor specificity of thoracic CT, which are currently the two most commonly used diagnostic tests for COVID-19 infection, make it difficult to draw definite conclusions about suspicious lesions on MRI.4 5 At the time of writing this report, all published examples of pulmonary COVID-19 on MRI are descriptive.6–8 The limited available data primarily from thoracic MRI, however, suggest that on liver and abdominal imaging protocols, COVID-19 presents as lung lesions with: high T1 signal due to partial alveolar collapse and higher tissue density, high T2 signal caused by oedema or consolidation, high DWI signal because of increased cell density from the inflammatory reaction and partial collapse, and with a heterogeneous enhancement pattern after contrast administration. There is a need for more reliable diagnostic tests and better descriptors of COVID-19 infection on common abdominal MRI sequences so that the correct management decisions can be made when incidental lesions are detected such as in the case of the patient described here.
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The lack of sensitivity of RT-PCR and the poor specificity of thoracic CT, which are currently the two most commonly used diagnostic tests for COVID-19 infection, make it difficult to draw definite conclusions about suspicious lesions on MRI.4 5 At the time of writing this report, all published examples of pulmonary COVID-19 on MRI are descriptive.6–8 The limited available data primarily from thoracic MRI, however, suggest that on liver and abdominal imaging protocols, COVID-19 presents as lung lesions with: high T1 signal due to partial alveolar collapse and higher tissue density, high T2 signal caused by oedema or consolidation, high DWI signal because of increased cell density from the inflammatory reaction and partial collapse, and with a heterogeneous enhancement pattern after contrast administration. There is a need for more reliable diagnostic tests and better descriptors of COVID-19 infection on common abdominal MRI sequences so that the correct management decisions can be made when incidental lesions are detected such as in the case of the patient described here.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2020-237430</identifier><identifier>PMID: 32690573</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd</publisher><subject>Case reports ; Clinical Laboratory Techniques ; Coronavirus Infections - diagnosis ; Coronavirus Infections - diagnostic imaging ; Coronaviruses ; COVID-19 ; COVID-19 Testing ; Diffusion Magnetic Resonance Imaging ; Fatty Liver - complications ; Fatty Liver - diagnostic imaging ; Female ; Global health ; Hemangioma - complications ; Hemangioma - diagnostic imaging ; Humans ; Images In ; Incidental Findings ; infections ; infectious diseases ; Injuries ; Liver Neoplasms - complications ; Liver Neoplasms - diagnostic imaging ; Lung - diagnostic imaging ; Lungs ; Magnetic Resonance Imaging ; Medical diagnosis ; Middle Aged ; Neoplasms, Multiple Primary - complications ; Neoplasms, Multiple Primary - diagnostic imaging ; Pandemics ; Pneumonia, Viral - diagnosis ; Pneumonia, Viral - diagnostic imaging ; radiology (diagnostics) ; respiratory system ; Reverse Transcriptase Polymerase Chain Reaction ; Sensitivity and Specificity ; Tomography, X-Ray Computed</subject><ispartof>BMJ case reports, 2020-07, Vol.13 (7), p.e237430</ispartof><rights>BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained. https://bmj.com/coronavirus/usage</rights><rights>BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. 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The lack of sensitivity of RT-PCR and the poor specificity of thoracic CT, which are currently the two most commonly used diagnostic tests for COVID-19 infection, make it difficult to draw definite conclusions about suspicious lesions on MRI.4 5 At the time of writing this report, all published examples of pulmonary COVID-19 on MRI are descriptive.6–8 The limited available data primarily from thoracic MRI, however, suggest that on liver and abdominal imaging protocols, COVID-19 presents as lung lesions with: high T1 signal due to partial alveolar collapse and higher tissue density, high T2 signal caused by oedema or consolidation, high DWI signal because of increased cell density from the inflammatory reaction and partial collapse, and with a heterogeneous enhancement pattern after contrast administration. 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subjects Case reports
Clinical Laboratory Techniques
Coronavirus Infections - diagnosis
Coronavirus Infections - diagnostic imaging
Coronaviruses
COVID-19
COVID-19 Testing
Diffusion Magnetic Resonance Imaging
Fatty Liver - complications
Fatty Liver - diagnostic imaging
Female
Global health
Hemangioma - complications
Hemangioma - diagnostic imaging
Humans
Images In
Incidental Findings
infections
infectious diseases
Injuries
Liver Neoplasms - complications
Liver Neoplasms - diagnostic imaging
Lung - diagnostic imaging
Lungs
Magnetic Resonance Imaging
Medical diagnosis
Middle Aged
Neoplasms, Multiple Primary - complications
Neoplasms, Multiple Primary - diagnostic imaging
Pandemics
Pneumonia, Viral - diagnosis
Pneumonia, Viral - diagnostic imaging
radiology (diagnostics)
respiratory system
Reverse Transcriptase Polymerase Chain Reaction
Sensitivity and Specificity
Tomography, X-Ray Computed
title Diagnostic challenges of incidental lung lesions on liver MRI during the COVID-19 pandemic
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