Post COVID-19 sequelae: venous thromboembolism complicated by lower GI bleed
On initial assessment, blood pressure was 120/90 mm Hg, pulse rate was 114 bpm, respiratory rate was 24 cycles/min and room air oxygen saturation was 89%. Renal function test revealed a prerenal pattern acute kidney injury (blood urea nitrogen 24 mg/dL and creatinine 1.3 mg/dL). COVID-19 infection i...
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description | On initial assessment, blood pressure was 120/90 mm Hg, pulse rate was 114 bpm, respiratory rate was 24 cycles/min and room air oxygen saturation was 89%. Renal function test revealed a prerenal pattern acute kidney injury (blood urea nitrogen 24 mg/dL and creatinine 1.3 mg/dL). COVID-19 infection is associated with hypercoagulability.1 Increased risk of developing deep vein thrombosis and pulmonary thromboembolism (cumulative incidence of 2.5%) has been noted in patients who have recovered from COVID-19.2 It has been advised to prescribe patients with oral anticoagulant for 30 days in those who have an increased risk for VTE.3 Our patient happens to be the first case to be reported in the clinical literature to have presented with both VTE and ongoing bleed while not on prophylactic anticoagulation. |
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Renal function test revealed a prerenal pattern acute kidney injury (blood urea nitrogen 24 mg/dL and creatinine 1.3 mg/dL). COVID-19 infection is associated with hypercoagulability.1 Increased risk of developing deep vein thrombosis and pulmonary thromboembolism (cumulative incidence of 2.5%) has been noted in patients who have recovered from COVID-19.2 It has been advised to prescribe patients with oral anticoagulant for 30 days in those who have an increased risk for VTE.3 Our patient happens to be the first case to be reported in the clinical literature to have presented with both VTE and ongoing bleed while not on prophylactic anticoagulation.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2020-241059</identifier><identifier>PMID: 33504542</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Aged ; Angiography, Digital Subtraction - methods ; Anticoagulants ; Anticoagulants - therapeutic use ; Blood clots ; Case reports ; Computed Tomography Angiography - methods ; Coronaviruses ; COVID-19 ; COVID-19 - complications ; Disease Progression ; Embolization, Therapeutic - methods ; Gastrointestinal Hemorrhage - diagnostic imaging ; Gastrointestinal Hemorrhage - etiology ; Gastrointestinal Hemorrhage - therapy ; Gastrointestinal Tract - diagnostic imaging ; Humans ; Images In ; Infections ; Intensive care ; Male ; Patients ; Pulmonary Artery - diagnostic imaging ; Pulmonary Embolism - diagnostic imaging ; Pulmonary Embolism - drug therapy ; Pulmonary Embolism - etiology ; SARS-CoV-2 ; Thromboembolism ; Thrombosis ; Treatment Outcome ; Veins & arteries</subject><ispartof>BMJ case reports, 2021-01, Vol.14 (1), p.e241059</ispartof><rights>BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained. https://bmj.com/coronavirus/usage?</rights><rights>BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b457t-c492daef99c329d831e196fbe86b7f3872e11878577c9640cd9ab2b69bce78593</citedby><cites>FETCH-LOGICAL-b457t-c492daef99c329d831e196fbe86b7f3872e11878577c9640cd9ab2b69bce78593</cites><orcidid>0000-0003-1193-9710</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577728/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577728/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33504542$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kumar, Malini Ashok</creatorcontrib><creatorcontrib>Krishnaswamy, Madhavan</creatorcontrib><creatorcontrib>Arul, Judah Nijas</creatorcontrib><title>Post COVID-19 sequelae: venous thromboembolism complicated by lower GI bleed</title><title>BMJ case reports</title><addtitle>BMJ Case Rep</addtitle><description>On initial assessment, blood pressure was 120/90 mm Hg, pulse rate was 114 bpm, respiratory rate was 24 cycles/min and room air oxygen saturation was 89%. Renal function test revealed a prerenal pattern acute kidney injury (blood urea nitrogen 24 mg/dL and creatinine 1.3 mg/dL). COVID-19 infection is associated with hypercoagulability.1 Increased risk of developing deep vein thrombosis and pulmonary thromboembolism (cumulative incidence of 2.5%) has been noted in patients who have recovered from COVID-19.2 It has been advised to prescribe patients with oral anticoagulant for 30 days in those who have an increased risk for VTE.3 Our patient happens to be the first case to be reported in the clinical literature to have presented with both VTE and ongoing bleed while not on prophylactic anticoagulation.</description><subject>Aged</subject><subject>Angiography, Digital Subtraction - methods</subject><subject>Anticoagulants</subject><subject>Anticoagulants - therapeutic use</subject><subject>Blood clots</subject><subject>Case reports</subject><subject>Computed Tomography Angiography - methods</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>COVID-19 - complications</subject><subject>Disease Progression</subject><subject>Embolization, Therapeutic - methods</subject><subject>Gastrointestinal Hemorrhage - diagnostic imaging</subject><subject>Gastrointestinal Hemorrhage - etiology</subject><subject>Gastrointestinal Hemorrhage - therapy</subject><subject>Gastrointestinal Tract - diagnostic imaging</subject><subject>Humans</subject><subject>Images In</subject><subject>Infections</subject><subject>Intensive care</subject><subject>Male</subject><subject>Patients</subject><subject>Pulmonary Artery - diagnostic imaging</subject><subject>Pulmonary Embolism - diagnostic imaging</subject><subject>Pulmonary Embolism - drug therapy</subject><subject>Pulmonary Embolism - etiology</subject><subject>SARS-CoV-2</subject><subject>Thromboembolism</subject><subject>Thrombosis</subject><subject>Treatment Outcome</subject><subject>Veins & arteries</subject><issn>1757-790X</issn><issn>1757-790X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkc9LHDEUx0NRqmw99yYBL1KYml8zmXgR2ep2YUEPbektJJk37iyZyZrMWvzvm2XtYr0YCAnJ53153_dF6DMlXynl1YV1sWCEkYIJSkr1AR1TWcpCKvL74NX9CJ2ktCJ5cSpqwT-iI85LIkrBjtHiPqQRT-9-zb8VVOEEjxvwBi7xEwxhk_C4jKG3AfL2XeqxC_3ad86M0GD7jH34AxHP5th6gOYTOmyNT3Dyck7Qz9ubH9PvxeJuNp9eLworSjkWTijWGGiVcpyppuYUqKpaC3VlZctryYDSWtallE5VgrhGGctspayD_Kr4BF3tdNcb20PjYBij8Xodu97EZx1Mp___GbqlfghPOo9JSsnqrHD-ohBDdpxG3XfJgfdmgGxbM1GzqiJ5hBk9e4OuwiYO2d-WqrhSQm5buthRLoaUIrT7bijR27R0Tktv09K7tHLF6WsTe_5fNhn4sgNsv3pX7S8dl5xh</recordid><startdate>20210127</startdate><enddate>20210127</enddate><creator>Kumar, Malini Ashok</creator><creator>Krishnaswamy, Madhavan</creator><creator>Arul, Judah Nijas</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-1193-9710</orcidid></search><sort><creationdate>20210127</creationdate><title>Post COVID-19 sequelae: venous thromboembolism complicated by lower GI bleed</title><author>Kumar, Malini Ashok ; Krishnaswamy, Madhavan ; Arul, Judah Nijas</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b457t-c492daef99c329d831e196fbe86b7f3872e11878577c9640cd9ab2b69bce78593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Aged</topic><topic>Angiography, Digital Subtraction - methods</topic><topic>Anticoagulants</topic><topic>Anticoagulants - therapeutic use</topic><topic>Blood clots</topic><topic>Case reports</topic><topic>Computed Tomography Angiography - methods</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>COVID-19 - complications</topic><topic>Disease Progression</topic><topic>Embolization, Therapeutic - methods</topic><topic>Gastrointestinal Hemorrhage - diagnostic imaging</topic><topic>Gastrointestinal Hemorrhage - etiology</topic><topic>Gastrointestinal Hemorrhage - therapy</topic><topic>Gastrointestinal Tract - diagnostic imaging</topic><topic>Humans</topic><topic>Images In</topic><topic>Infections</topic><topic>Intensive care</topic><topic>Male</topic><topic>Patients</topic><topic>Pulmonary Artery - diagnostic imaging</topic><topic>Pulmonary Embolism - diagnostic imaging</topic><topic>Pulmonary Embolism - drug therapy</topic><topic>Pulmonary Embolism - etiology</topic><topic>SARS-CoV-2</topic><topic>Thromboembolism</topic><topic>Thrombosis</topic><topic>Treatment Outcome</topic><topic>Veins & arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kumar, Malini Ashok</creatorcontrib><creatorcontrib>Krishnaswamy, Madhavan</creatorcontrib><creatorcontrib>Arul, Judah Nijas</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kumar, Malini Ashok</au><au>Krishnaswamy, Madhavan</au><au>Arul, Judah Nijas</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Post COVID-19 sequelae: venous thromboembolism complicated by lower GI bleed</atitle><jtitle>BMJ case reports</jtitle><addtitle>BMJ Case Rep</addtitle><date>2021-01-27</date><risdate>2021</risdate><volume>14</volume><issue>1</issue><spage>e241059</spage><pages>e241059-</pages><issn>1757-790X</issn><eissn>1757-790X</eissn><abstract>On initial assessment, blood pressure was 120/90 mm Hg, pulse rate was 114 bpm, respiratory rate was 24 cycles/min and room air oxygen saturation was 89%. Renal function test revealed a prerenal pattern acute kidney injury (blood urea nitrogen 24 mg/dL and creatinine 1.3 mg/dL). COVID-19 infection is associated with hypercoagulability.1 Increased risk of developing deep vein thrombosis and pulmonary thromboembolism (cumulative incidence of 2.5%) has been noted in patients who have recovered from COVID-19.2 It has been advised to prescribe patients with oral anticoagulant for 30 days in those who have an increased risk for VTE.3 Our patient happens to be the first case to be reported in the clinical literature to have presented with both VTE and ongoing bleed while not on prophylactic anticoagulation.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>33504542</pmid><doi>10.1136/bcr-2020-241059</doi><orcidid>https://orcid.org/0000-0003-1193-9710</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Aged Angiography, Digital Subtraction - methods Anticoagulants Anticoagulants - therapeutic use Blood clots Case reports Computed Tomography Angiography - methods Coronaviruses COVID-19 COVID-19 - complications Disease Progression Embolization, Therapeutic - methods Gastrointestinal Hemorrhage - diagnostic imaging Gastrointestinal Hemorrhage - etiology Gastrointestinal Hemorrhage - therapy Gastrointestinal Tract - diagnostic imaging Humans Images In Infections Intensive care Male Patients Pulmonary Artery - diagnostic imaging Pulmonary Embolism - diagnostic imaging Pulmonary Embolism - drug therapy Pulmonary Embolism - etiology SARS-CoV-2 Thromboembolism Thrombosis Treatment Outcome Veins & arteries |
title | Post COVID-19 sequelae: venous thromboembolism complicated by lower GI bleed |
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