LncRP11-675F6.3 responds to rapamycin treatment and reduces triglyceride accumulation via interacting with HK1 in hepatocytes by regulating autophagy and VLDL-related proteins: LncRNA with HK1 regulates triglycerides, autophagy and VLDL

Long noncoding RNAs (lncRNAs) have been widely proven to be involved in liver lipid homeostasis. Herein, we identify an upregulated lncRNA named lncRP11-675F6.3 in response to rapamycin treatment using a microarray in HepG2 cells. Knockdown of lncRP11-675F6 . 3 leads to a significant reduction in ap...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Acta biochimica et biophysica Sinica 2023-05, Vol.55 (10), p.1606-1617
Hauptverfasser:	Wang, Lingling, Fang, Xiaojuan, Yang, Ziyou, Li, Xueling, Cheng, Mengdi, Cheng, Liang, Wang, Ganglin, Li, Wei, Liu, Lin
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!