Computational Description of Alkylated Iron–Sulfur Organometallic Clusters

The radical S-adenosyl methionine (SAM) enzyme superfamily has widespread roles in hydrogen atom abstraction reactions of crucial biological importance. In these enzymes, reductive cleavage of SAM bound to a [4Fe-4S]1+ cluster generates the 5′-deoxyadenosyl radical (5′-dAdo•) which ultimately abstra...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of the American Chemical Society 2023-06, Vol.145 (25), p.13879-13887
Hauptverfasser:	Jodts, Richard J., Wittkop, M, Ho, Madeline B., Broderick, William E., Broderick, Joan B., Hoffman, Brian M., Mosquera, Martín A.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!