Ibrutinib Induces a Dramatic Improvement for Idiopathic Refractory Ascites Following Allogeneic Hematopoietic Cell Transplantation
We herein report a case of idiopathic refractory ascites following allogeneic hematopoietic cell transplantation that was successfully treated with ibrutinib. A 39-year-old man presented with massive transudative ascites. Despite a high portal venous pressure, the liver histology showed traces of al...
Gespeichert in:
| Veröffentlicht in: | Internal Medicine 2023, pp.1139-22 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2741 |
|---|---|
| container_issue | 18 |
| container_start_page | 1139-22 |
| container_title | Internal Medicine |
| container_volume | 62 |
| creator | Tazoe, Kumiyo Nishimoto, Mitsutaka Yamamoto, Akira Makuuchi, Yosuke Kuno, Masatomo Okamura, Hiroshi Nakashima, Yasuhiro Tanaka, Sayaka Ohsawa, Masahiko Hino, Masayuki Nakamae, Hirohisa |
| description | We herein report a case of idiopathic refractory ascites following allogeneic hematopoietic cell transplantation that was successfully treated with ibrutinib. A 39-year-old man presented with massive transudative ascites. Despite a high portal venous pressure, the liver histology showed traces of alloreactivity inconsistent with veno-occlusive disease/sinusoidal obstructive syndrome. Ibrutinib was administered for ascites possibly secondary to portal hypertension associated with the alloreactivity. The ascites dramatically improved, and the portal venous pressure was reduced. This case may help clarify the mechanism through which refractory ascites develops after allogeneic hematopoietic cell transplantation and establish appropriate treatment protocols. |
| doi_str_mv | 10.2169/internalmedicine.1139-22 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10569935</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2774896524</sourcerecordid><originalsourceid>FETCH-LOGICAL-c664t-524fa9c97fe0fffa66d2539ea794d6e5f9c4260173603537bf9837f48b465afa3</originalsourceid><addsrcrecordid>eNplkUGP0zAQhS0EYkvhL6BIXLhkcezEjk-oKiwbaSUktHC1po7dukrsYDtFe-WX46rdCpaLbWm-92bGD6GiwtekYuKDdUkHB8Ooe6us09dVRUVJyDO0qGgtSk5o8xwtsKjakuTjCr2KcY8xbbkgL9EVZbypa9ws0O9uE-Zknd0UnetnpWMBxacAIySrim6cgj_oUbtUGB-Krrd-grTLpW_aBFDJh4diFZVNWXjjh8H_sm5brPJjq53O3K3OVn7yVh8N13oYivsALk4DuJSbePcavTAwRP3mfC_R95vP9-vb8u7rl269uisVY3UqG1IbEEpwo7ExBhjrSUOFBi7qnunGCFUThitOGaYN5RsjWspN3W5q1oABukQfT77TvMkfp_JSAQY5BTtCeJAerPy34uxObv1BVrhhQmTPJXp_dgj-56xjkqONKq8ETvs5SsJ53QqWJ83ouyfo3s_HyDLVco5bTNo2U-2JUsHHGLS5TFNheUxaPk1aHpOWhGTp27-3uQgfo83AjxOwjwm2-gJAyEEM-n9n6A_ZS-LHx7nTRaB2EKR29A90Ec7m</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2877080288</pqid></control><display><type>article</type><title>Ibrutinib Induces a Dramatic Improvement for Idiopathic Refractory Ascites Following Allogeneic Hematopoietic Cell Transplantation</title><source>J-STAGE Free</source><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Tazoe, Kumiyo ; Nishimoto, Mitsutaka ; Yamamoto, Akira ; Makuuchi, Yosuke ; Kuno, Masatomo ; Okamura, Hiroshi ; Nakashima, Yasuhiro ; Tanaka, Sayaka ; Ohsawa, Masahiko ; Hino, Masayuki ; Nakamae, Hirohisa</creator><creatorcontrib>Tazoe, Kumiyo ; Nishimoto, Mitsutaka ; Yamamoto, Akira ; Makuuchi, Yosuke ; Kuno, Masatomo ; Okamura, Hiroshi ; Nakashima, Yasuhiro ; Tanaka, Sayaka ; Ohsawa, Masahiko ; Hino, Masayuki ; Nakamae, Hirohisa</creatorcontrib><description>We herein report a case of idiopathic refractory ascites following allogeneic hematopoietic cell transplantation that was successfully treated with ibrutinib. A 39-year-old man presented with massive transudative ascites. Despite a high portal venous pressure, the liver histology showed traces of alloreactivity inconsistent with veno-occlusive disease/sinusoidal obstructive syndrome. Ibrutinib was administered for ascites possibly secondary to portal hypertension associated with the alloreactivity. The ascites dramatically improved, and the portal venous pressure was reduced. This case may help clarify the mechanism through which refractory ascites develops after allogeneic hematopoietic cell transplantation and establish appropriate treatment protocols.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.1139-22</identifier><identifier>PMID: 36754405</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Allografts ; Ascites ; Case Report ; Case reports ; hematopoietic cell transplantation ; Hematopoietic stem cells ; ibrutinib ; Internal medicine ; portal hypertension ; refractory ascites ; Transplantation ; Veno-occlusive disease</subject><ispartof>Internal Medicine, 2023, pp.1139-22</ispartof><rights>2023 by The Japanese Society of Internal Medicine</rights><rights>Copyright Japan Science and Technology Agency 2023</rights><rights>Copyright © 2023 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c664t-524fa9c97fe0fffa66d2539ea794d6e5f9c4260173603537bf9837f48b465afa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569935/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569935/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,1876,27903,27904,53770,53772</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36754405$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tazoe, Kumiyo</creatorcontrib><creatorcontrib>Nishimoto, Mitsutaka</creatorcontrib><creatorcontrib>Yamamoto, Akira</creatorcontrib><creatorcontrib>Makuuchi, Yosuke</creatorcontrib><creatorcontrib>Kuno, Masatomo</creatorcontrib><creatorcontrib>Okamura, Hiroshi</creatorcontrib><creatorcontrib>Nakashima, Yasuhiro</creatorcontrib><creatorcontrib>Tanaka, Sayaka</creatorcontrib><creatorcontrib>Ohsawa, Masahiko</creatorcontrib><creatorcontrib>Hino, Masayuki</creatorcontrib><creatorcontrib>Nakamae, Hirohisa</creatorcontrib><title>Ibrutinib Induces a Dramatic Improvement for Idiopathic Refractory Ascites Following Allogeneic Hematopoietic Cell Transplantation</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>We herein report a case of idiopathic refractory ascites following allogeneic hematopoietic cell transplantation that was successfully treated with ibrutinib. A 39-year-old man presented with massive transudative ascites. Despite a high portal venous pressure, the liver histology showed traces of alloreactivity inconsistent with veno-occlusive disease/sinusoidal obstructive syndrome. Ibrutinib was administered for ascites possibly secondary to portal hypertension associated with the alloreactivity. The ascites dramatically improved, and the portal venous pressure was reduced. This case may help clarify the mechanism through which refractory ascites develops after allogeneic hematopoietic cell transplantation and establish appropriate treatment protocols.</description><subject>Allografts</subject><subject>Ascites</subject><subject>Case Report</subject><subject>Case reports</subject><subject>hematopoietic cell transplantation</subject><subject>Hematopoietic stem cells</subject><subject>ibrutinib</subject><subject>Internal medicine</subject><subject>portal hypertension</subject><subject>refractory ascites</subject><subject>Transplantation</subject><subject>Veno-occlusive disease</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNplkUGP0zAQhS0EYkvhL6BIXLhkcezEjk-oKiwbaSUktHC1po7dukrsYDtFe-WX46rdCpaLbWm-92bGD6GiwtekYuKDdUkHB8Ooe6us09dVRUVJyDO0qGgtSk5o8xwtsKjakuTjCr2KcY8xbbkgL9EVZbypa9ws0O9uE-Zknd0UnetnpWMBxacAIySrim6cgj_oUbtUGB-Krrd-grTLpW_aBFDJh4diFZVNWXjjh8H_sm5brPJjq53O3K3OVn7yVh8N13oYivsALk4DuJSbePcavTAwRP3mfC_R95vP9-vb8u7rl269uisVY3UqG1IbEEpwo7ExBhjrSUOFBi7qnunGCFUThitOGaYN5RsjWspN3W5q1oABukQfT77TvMkfp_JSAQY5BTtCeJAerPy34uxObv1BVrhhQmTPJXp_dgj-56xjkqONKq8ETvs5SsJ53QqWJ83ouyfo3s_HyDLVco5bTNo2U-2JUsHHGLS5TFNheUxaPk1aHpOWhGTp27-3uQgfo83AjxOwjwm2-gJAyEEM-n9n6A_ZS-LHx7nTRaB2EKR29A90Ec7m</recordid><startdate>20230915</startdate><enddate>20230915</enddate><creator>Tazoe, Kumiyo</creator><creator>Nishimoto, Mitsutaka</creator><creator>Yamamoto, Akira</creator><creator>Makuuchi, Yosuke</creator><creator>Kuno, Masatomo</creator><creator>Okamura, Hiroshi</creator><creator>Nakashima, Yasuhiro</creator><creator>Tanaka, Sayaka</creator><creator>Ohsawa, Masahiko</creator><creator>Hino, Masayuki</creator><creator>Nakamae, Hirohisa</creator><general>The Japanese Society of Internal Medicine</general><general>Japan Science and Technology Agency</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20230915</creationdate><title>Ibrutinib Induces a Dramatic Improvement for Idiopathic Refractory Ascites Following Allogeneic Hematopoietic Cell Transplantation</title><author>Tazoe, Kumiyo ; Nishimoto, Mitsutaka ; Yamamoto, Akira ; Makuuchi, Yosuke ; Kuno, Masatomo ; Okamura, Hiroshi ; Nakashima, Yasuhiro ; Tanaka, Sayaka ; Ohsawa, Masahiko ; Hino, Masayuki ; Nakamae, Hirohisa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c664t-524fa9c97fe0fffa66d2539ea794d6e5f9c4260173603537bf9837f48b465afa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Allografts</topic><topic>Ascites</topic><topic>Case Report</topic><topic>Case reports</topic><topic>hematopoietic cell transplantation</topic><topic>Hematopoietic stem cells</topic><topic>ibrutinib</topic><topic>Internal medicine</topic><topic>portal hypertension</topic><topic>refractory ascites</topic><topic>Transplantation</topic><topic>Veno-occlusive disease</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tazoe, Kumiyo</creatorcontrib><creatorcontrib>Nishimoto, Mitsutaka</creatorcontrib><creatorcontrib>Yamamoto, Akira</creatorcontrib><creatorcontrib>Makuuchi, Yosuke</creatorcontrib><creatorcontrib>Kuno, Masatomo</creatorcontrib><creatorcontrib>Okamura, Hiroshi</creatorcontrib><creatorcontrib>Nakashima, Yasuhiro</creatorcontrib><creatorcontrib>Tanaka, Sayaka</creatorcontrib><creatorcontrib>Ohsawa, Masahiko</creatorcontrib><creatorcontrib>Hino, Masayuki</creatorcontrib><creatorcontrib>Nakamae, Hirohisa</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tazoe, Kumiyo</au><au>Nishimoto, Mitsutaka</au><au>Yamamoto, Akira</au><au>Makuuchi, Yosuke</au><au>Kuno, Masatomo</au><au>Okamura, Hiroshi</au><au>Nakashima, Yasuhiro</au><au>Tanaka, Sayaka</au><au>Ohsawa, Masahiko</au><au>Hino, Masayuki</au><au>Nakamae, Hirohisa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ibrutinib Induces a Dramatic Improvement for Idiopathic Refractory Ascites Following Allogeneic Hematopoietic Cell Transplantation</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2023-09-15</date><risdate>2023</risdate><volume>62</volume><issue>18</issue><spage>1139-22</spage><epage>2741</epage><pages>1139-22-2741</pages><artnum>1139-22</artnum><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>We herein report a case of idiopathic refractory ascites following allogeneic hematopoietic cell transplantation that was successfully treated with ibrutinib. A 39-year-old man presented with massive transudative ascites. Despite a high portal venous pressure, the liver histology showed traces of alloreactivity inconsistent with veno-occlusive disease/sinusoidal obstructive syndrome. Ibrutinib was administered for ascites possibly secondary to portal hypertension associated with the alloreactivity. The ascites dramatically improved, and the portal venous pressure was reduced. This case may help clarify the mechanism through which refractory ascites develops after allogeneic hematopoietic cell transplantation and establish appropriate treatment protocols.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>36754405</pmid><doi>10.2169/internalmedicine.1139-22</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0918-2918 |
| ispartof | Internal Medicine, 2023, pp.1139-22 |
| issn | 0918-2918 1349-7235 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10569935 |
| source | J-STAGE Free; PubMed Central Open Access; PubMed Central |
| subjects | Allografts Ascites Case Report Case reports hematopoietic cell transplantation Hematopoietic stem cells ibrutinib Internal medicine portal hypertension refractory ascites Transplantation Veno-occlusive disease |
| title | Ibrutinib Induces a Dramatic Improvement for Idiopathic Refractory Ascites Following Allogeneic Hematopoietic Cell Transplantation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T05%3A42%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Ibrutinib%20Induces%20a%20Dramatic%20Improvement%20for%20Idiopathic%20Refractory%20Ascites%20Following%20Allogeneic%20Hematopoietic%20Cell%20Transplantation&rft.jtitle=Internal%20Medicine&rft.au=Tazoe,%20Kumiyo&rft.date=2023-09-15&rft.volume=62&rft.issue=18&rft.spage=1139-22&rft.epage=2741&rft.pages=1139-22-2741&rft.artnum=1139-22&rft.issn=0918-2918&rft.eissn=1349-7235&rft_id=info:doi/10.2169/internalmedicine.1139-22&rft_dat=%3Cproquest_pubme%3E2774896524%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2877080288&rft_id=info:pmid/36754405&rfr_iscdi=true |