Differentiation of Cancer Stem Cells through Nanoparticle Surface Engineering

Cancer stem cells (CSCs) are a crucial therapeutic target because of their role in resistance to chemo- and radiation therapy, metastasis, and tumor recurrence. Differentiation therapy presents a potential strategy for “defanging” CSCs. To date, only a limited number of small-molecule and nanomateri...

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Veröffentlicht in:ACS nano 2020-11, Vol.14 (11), p.15276-15285
Hauptverfasser: Geng, Yingying, Amante, John J, Goel, Hira L, Zhang, Xianzhi, Walker, Melanie R, Luther, David C, Mercurio, Arthur M, Rotello, Vincent M
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Sprache:eng
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