Skewing cPLA2 activity toward oxoeicosanoid production promotes neutrophil N2 polarization, wound healing, and the response to sepsis

Uncontrolled inflammation is linked to poor outcomes in sepsis and wound healing, both of which proceed through distinct inflammatory and resolution phases. Eicosanoids are a class of bioactive lipids that recruit neutrophils and other innate immune cells. The interaction of ceramide 1-phosphate (C1...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Science signaling 2023-07, Vol.16 (793), p.eadd6527-eadd6527
Hauptverfasser:	Maus, Kenneth D., Stephenson, Daniel J., Macknight, H. Patrick, Vu, Ngoc T., Hoeferlin, L. Alexis, Kim, Minjung, Diegelmann, Robert F., Xie, Xiujie, Chalfant, Charles E.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!