Preoperative frailty as a predictive factor for postoperative complications in patients with pancreatic cancer
Frailty is considered one of the most important indicators of a patient's general condition. However, only a few studies have investigated the association between preoperative frailty and postoperative complications in pancreatic cancer. Therefore, this study aimed to examine this association i...
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| Veröffentlicht in: | Nagoya journal of medical science 2023-08, Vol.85 (3), p.518-527 |
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| container_title | Nagoya journal of medical science |
| container_volume | 85 |
| creator | Onji, Makoto Kakizoe, Shinji Naito, Koichi Date, Kenjiro Nakai, Asuka Shimizu, Kanami Suyama, Masatake Nakamura, So Kuga, Hirotaka Nishihara, Kazuyoshi |
| description | Frailty is considered one of the most important indicators of a patient's general condition. However, only a few studies have investigated the association between preoperative frailty and postoperative complications in pancreatic cancer. Therefore, this study aimed to examine this association in patients with pancreatic cancer. We retrospectively reviewed 52 consecutive patients who underwent pancreatectomy for pancreatic cancer between July 2019 and March 2021. Patients were classified into two groups according to the presence of postoperative complications. Their characteristics and clinical parameters, including physical function, were analyzed. Patients with postoperative complications had a higher prevalence of frailty (58.8% vs 14.3%,
= 0.003) and a shorter 6-min walk distance (380 m vs 436 m,
= 0.020) than those without postoperative complications. Logistic regression analysis identified preoperative frailty as the only independent risk factor for complications after pancreatectomy (
= 0.002). Preoperative frailty is associated with postoperative complications of pancreatectomy. Since preoperative frailty can be easily evaluated, it is a useful predictor of postoperative complications after pancreatectomy. |
| doi_str_mv | 10.18999/nagjms.85.3.518 |
| format | Article |
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= 0.003) and a shorter 6-min walk distance (380 m vs 436 m,
= 0.020) than those without postoperative complications. Logistic regression analysis identified preoperative frailty as the only independent risk factor for complications after pancreatectomy (
= 0.002). Preoperative frailty is associated with postoperative complications of pancreatectomy. Since preoperative frailty can be easily evaluated, it is a useful predictor of postoperative complications after pancreatectomy.</description><identifier>ISSN: 0027-7622</identifier><identifier>EISSN: 2186-3326</identifier><identifier>DOI: 10.18999/nagjms.85.3.518</identifier><identifier>PMID: 37829477</identifier><language>eng</language><publisher>Japan: Nagoya University</publisher><subject>Frailty - diagnosis ; Frailty - epidemiology ; Humans ; Original Paper ; Pancreatic Neoplasms ; Pancreatic Neoplasms - surgery ; Postoperative Complications - epidemiology ; Postoperative Complications - etiology ; Retrospective Studies ; Risk Factors</subject><ispartof>Nagoya journal of medical science, 2023-08, Vol.85 (3), p.518-527</ispartof><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565590/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565590/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37829477$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Onji, Makoto</creatorcontrib><creatorcontrib>Kakizoe, Shinji</creatorcontrib><creatorcontrib>Naito, Koichi</creatorcontrib><creatorcontrib>Date, Kenjiro</creatorcontrib><creatorcontrib>Nakai, Asuka</creatorcontrib><creatorcontrib>Shimizu, Kanami</creatorcontrib><creatorcontrib>Suyama, Masatake</creatorcontrib><creatorcontrib>Nakamura, So</creatorcontrib><creatorcontrib>Kuga, Hirotaka</creatorcontrib><creatorcontrib>Nishihara, Kazuyoshi</creatorcontrib><title>Preoperative frailty as a predictive factor for postoperative complications in patients with pancreatic cancer</title><title>Nagoya journal of medical science</title><addtitle>Nagoya J Med Sci</addtitle><description>Frailty is considered one of the most important indicators of a patient's general condition. However, only a few studies have investigated the association between preoperative frailty and postoperative complications in pancreatic cancer. Therefore, this study aimed to examine this association in patients with pancreatic cancer. We retrospectively reviewed 52 consecutive patients who underwent pancreatectomy for pancreatic cancer between July 2019 and March 2021. Patients were classified into two groups according to the presence of postoperative complications. Their characteristics and clinical parameters, including physical function, were analyzed. Patients with postoperative complications had a higher prevalence of frailty (58.8% vs 14.3%,
= 0.003) and a shorter 6-min walk distance (380 m vs 436 m,
= 0.020) than those without postoperative complications. Logistic regression analysis identified preoperative frailty as the only independent risk factor for complications after pancreatectomy (
= 0.002). Preoperative frailty is associated with postoperative complications of pancreatectomy. Since preoperative frailty can be easily evaluated, it is a useful predictor of postoperative complications after pancreatectomy.</description><subject>Frailty - diagnosis</subject><subject>Frailty - epidemiology</subject><subject>Humans</subject><subject>Original Paper</subject><subject>Pancreatic Neoplasms</subject><subject>Pancreatic Neoplasms - surgery</subject><subject>Postoperative Complications - epidemiology</subject><subject>Postoperative Complications - etiology</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><issn>0027-7622</issn><issn>2186-3326</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVUMlKBDEQDaI47ejdk-QHus3SSTonkcENBvSg5yaTZSZDLyFpR-bvDYzroaj3qniPegXAJUYVbqSU14Nab_tUNayiFcPNESgIbnhJKeHHoECIiFJwQmbgLKUtQrWUSJ6CGRUNkbUQBRheoh2DjWryOwtdVL6b9lAlqGCI1nh9mCs9jRG6XGFM069Aj33ovM5kHBL0AwwZ2mFK8MNPm8wGHW0eaagztPEcnDjVJXvx1efg7f7udfFYLp8fnha3y3JbIzyVNIdruCPI6EY6vRKEC-YEs0zU0mGDTS0MQxTlGFQb55ByThislaSMC0fn4ObgG95XvTU6nxRV14boexX37ah8-38z-E27HnctRowzJlF2uPrr8CP9fh39BECydjk</recordid><startdate>20230801</startdate><enddate>20230801</enddate><creator>Onji, Makoto</creator><creator>Kakizoe, Shinji</creator><creator>Naito, Koichi</creator><creator>Date, Kenjiro</creator><creator>Nakai, Asuka</creator><creator>Shimizu, Kanami</creator><creator>Suyama, Masatake</creator><creator>Nakamura, So</creator><creator>Kuga, Hirotaka</creator><creator>Nishihara, Kazuyoshi</creator><general>Nagoya University</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>5PM</scope></search><sort><creationdate>20230801</creationdate><title>Preoperative frailty as a predictive factor for postoperative complications in patients with pancreatic cancer</title><author>Onji, Makoto ; Kakizoe, Shinji ; Naito, Koichi ; Date, Kenjiro ; Nakai, Asuka ; Shimizu, Kanami ; Suyama, Masatake ; Nakamura, So ; Kuga, Hirotaka ; Nishihara, Kazuyoshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j401t-389986f20dc89fcb72675f75e5749f1d1d47d50308293cdff0aff7d1ca93567f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Frailty - diagnosis</topic><topic>Frailty - epidemiology</topic><topic>Humans</topic><topic>Original Paper</topic><topic>Pancreatic Neoplasms</topic><topic>Pancreatic Neoplasms - surgery</topic><topic>Postoperative Complications - epidemiology</topic><topic>Postoperative Complications - etiology</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><toplevel>online_resources</toplevel><creatorcontrib>Onji, Makoto</creatorcontrib><creatorcontrib>Kakizoe, Shinji</creatorcontrib><creatorcontrib>Naito, Koichi</creatorcontrib><creatorcontrib>Date, Kenjiro</creatorcontrib><creatorcontrib>Nakai, Asuka</creatorcontrib><creatorcontrib>Shimizu, Kanami</creatorcontrib><creatorcontrib>Suyama, Masatake</creatorcontrib><creatorcontrib>Nakamura, So</creatorcontrib><creatorcontrib>Kuga, Hirotaka</creatorcontrib><creatorcontrib>Nishihara, Kazuyoshi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nagoya journal of medical science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Onji, Makoto</au><au>Kakizoe, Shinji</au><au>Naito, Koichi</au><au>Date, Kenjiro</au><au>Nakai, Asuka</au><au>Shimizu, Kanami</au><au>Suyama, Masatake</au><au>Nakamura, So</au><au>Kuga, Hirotaka</au><au>Nishihara, Kazuyoshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preoperative frailty as a predictive factor for postoperative complications in patients with pancreatic cancer</atitle><jtitle>Nagoya journal of medical science</jtitle><addtitle>Nagoya J Med Sci</addtitle><date>2023-08-01</date><risdate>2023</risdate><volume>85</volume><issue>3</issue><spage>518</spage><epage>527</epage><pages>518-527</pages><issn>0027-7622</issn><eissn>2186-3326</eissn><abstract>Frailty is considered one of the most important indicators of a patient's general condition. However, only a few studies have investigated the association between preoperative frailty and postoperative complications in pancreatic cancer. Therefore, this study aimed to examine this association in patients with pancreatic cancer. We retrospectively reviewed 52 consecutive patients who underwent pancreatectomy for pancreatic cancer between July 2019 and March 2021. Patients were classified into two groups according to the presence of postoperative complications. Their characteristics and clinical parameters, including physical function, were analyzed. Patients with postoperative complications had a higher prevalence of frailty (58.8% vs 14.3%,
= 0.003) and a shorter 6-min walk distance (380 m vs 436 m,
= 0.020) than those without postoperative complications. Logistic regression analysis identified preoperative frailty as the only independent risk factor for complications after pancreatectomy (
= 0.002). Preoperative frailty is associated with postoperative complications of pancreatectomy. Since preoperative frailty can be easily evaluated, it is a useful predictor of postoperative complications after pancreatectomy.</abstract><cop>Japan</cop><pub>Nagoya University</pub><pmid>37829477</pmid><doi>10.18999/nagjms.85.3.518</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Freely Accessible Japanese Titles; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection; PubMed Central Open Access |
| subjects | Frailty - diagnosis Frailty - epidemiology Humans Original Paper Pancreatic Neoplasms Pancreatic Neoplasms - surgery Postoperative Complications - epidemiology Postoperative Complications - etiology Retrospective Studies Risk Factors |
| title | Preoperative frailty as a predictive factor for postoperative complications in patients with pancreatic cancer |
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