Placenta mesenchymal stem cell-derived extracellular vesicles alleviate liver fibrosis by inactivating hepatic stellate cells through a miR-378c/SKP2 axis

Background Extracellular vesicles derived from mesenchymal stem/stromal cells (MSCs) have shown therapeutic effects on liver fibrosis. This study aimed to evaluate the effects of extracellular vesicles from placenta-derived MSCs (Pd-MSCs-EVs) on liver fibrosis at 3D/2D levels and explore the potenti...

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Veröffentlicht in:	Inflammation and Regeneration 2023-10, Vol.43 (1), p.47-47, Article 47
Hauptverfasser:	Zheng, Wenjie, Bian, Saiyan, Qiu, Shi, Bishop, Colin E., Wan, Meimei, Xu, Nuo, Sun, Xieyin, Sequeira, Russel Clive, Atala, Anthony, Gu, Zhifeng, Zhao, Weixin
Format:	Artikel
Sprache:	eng
Schlagworte:	Extracellular vesicles Fibrosis Health aspects Ligases Liver diseases Liver fibrosis Mesenchymal stem/stromal cells miR-378c Multicellular organoids Palladium Physiological aspects Scientific equipment and supplies industry Stem cells Transforming growth factors
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