Colorectal cancer organoid-stroma biobank allows subtype-specific assessment of individualized therapy responses

In colorectal cancers (CRC) the tumor microenvironment plays a key role for prognosis and therapy efficacy. Patient-derived tumor organoids (PDTOs) show enormous potential for preclinical testing, however, cultured tumor cells lose important characteristics including the 'consensus molecular su...

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Veröffentlicht in:	Cancer discovery 2023-10, Vol.13 (10), p.2192-2211
Hauptverfasser:	Farin, Henner F, Mosa, Mohammed H, Ndreshkjana, Benardina, Grebbin, Britta M, Ritter, Birgit, Menche, Constantin, Kennel, Kilian B, Ziegler, Paul K, Szabo, Lili, Bollrath, Julia, Rieder, Dietmar, Michels, Birgitta E, Kress, Alena, Bozlar, Muge, Darvishi, Tahmineh, Stier, Sara, Kur, Ivan-Maximiliano, Bankov, Katrin, Kesselring, Rebecca, Fichtner-Feigl, Stefan, Brune, Bernhard, Goetze, Thorsten O, Al-Batran, Salah-Eddin, Brandts, Christian H, Bechstein, Wolf O, Wild, Peter J, Weigert, Andreas, Muller, Susanne, Knapp, Stefan, Trajanoski, Zlatko, Greten, Florian R
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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