Lysyl oxidase-like 2 promotes stemness and enhances antitumor effects of gefitinib in head and neck cancer via IFIT1 and IFIT3

Lysyl oxidase-like 2 (LOXL2) is a matrix-remodeling enzyme that has recently been identified as an important regulator of tumor progression and metastasis. This study discovered that LOXL2 expression in oral squamous cell carcinoma (OSCC) tissues was significantly associated with tumor clinical stag...

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Veröffentlicht in:Cancer science 2023-10, Vol.114 (10), p.3957-3971
Hauptverfasser: Lu, Yi-Jie, Deng, Yi-Ting, Ko, Hui-Hsin, Peng, Hsin-Hui, Lee, Hsiang-Chieh, Kuo, Mark Yen-Ping, Cheng, Shih-Jung
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Sprache:eng
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