Feasibility and outcomes of living-donor liver transplantation utilizing the right hemi-liver graft with portal vein anatomical variations
Purpose Portal vein (PV) reconstruction is a key factor for successful living-donor liver transplantation (LDLT). Anatomical variations of right PV (RPV) are encountered among potential donors. Methods To evaluate a single center experience of reconstruction techniques for the right hemi-liver graft...
Gespeichert in:
| Veröffentlicht in: | Langenbeck's archives of surgery 2023-10, Vol.408 (1), p.387-387, Article 387 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 387 |
|---|---|
| container_issue | 1 |
| container_start_page | 387 |
| container_title | Langenbeck's archives of surgery |
| container_volume | 408 |
| creator | Shehta, Ahmed Elshobari, Mohamed Salah, Tarek Sultan, Ahmad M. Yasen, Amr Shiha, Usama El-Saadany, Mohamed Monier, Ahmed Said, Rami Habl, Mohamed S. Adly, Reham El Ged, Basma Abd Elmoaem Karam, Rasha Khaled, Reem El Razek, Hassan Magdy Abd Abdel-Khalek, Ehab E. Wahab, Mohamed Abdel |
| description | Purpose
Portal vein (PV) reconstruction is a key factor for successful living-donor liver transplantation (LDLT). Anatomical variations of right PV (RPV) are encountered among potential donors.
Methods
To evaluate a single center experience of reconstruction techniques for the right hemi-liver grafts with PV variations during the period between May 2004 and 2022.
Results
A total of 915 recipients underwent LDLT, among them 52 (5.8%) had RPV anatomical variations. Type II PV was found in 7 cases (13.5%), which were reconstructed by direct venoplasty. Type III PV was found in 27 cases (51.9%). They were reconstructed by direct venoplasty in 2 cases (3.8%), Y graft interposition in 2 cases (3.8%), and in situ double PV anastomoses in 23 cases (44.2%). Type IV PV was found in 18 cases (34.6%) and was reconstructed by Y graft interposition in 9 cases (17.3%), and in situ double PV anastomoses in 9 cases (17.3%).
Early right posterior PV stenosis occurred in 2 recipients (3.8%). Early PV thrombosis occurred in 3 recipients (5.8%). The median follow-up duration was 54.5 months (4 – 185). The 1-, 3-, and 5-years survival rates were 91.9%, 86%, and 81.2%, respectively. Late PV stenosis occurred in 2 recipients (3.8%) and was managed conservatively.
Conclusion
Utilization of potential living donors with RPV anatomic variations may help to expand the donor pool. We found that direct venoplasty and in situ dual PV anastomoses techniques were safe, feasible, and associated with successful outcomes. |
| doi_str_mv | 10.1007/s00423-023-03115-9 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10550851</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2872804148</sourcerecordid><originalsourceid>FETCH-LOGICAL-c398t-1f96fbfb83a4b6967cf683741e1a5f9e91bf4bdd590580a4b95e97082405372d3</originalsourceid><addsrcrecordid>eNp9kUFvFiEQhomxsbXtH_BgOHpZHRZYlpMxjVWTJl7qmbC7sEuzC5_Afqb-BH-1rFubevEwgck88w7Mi9ArAm8JgHiXAFhNK9iCEsIr-QydEUZ5VTNOnj-5n6KXKd0BQCMke4FOqRCyBkbP0K9ro5Pr3OzyPdZ-wGHNfVhMwsHi2R2dH6sh-BC3xESco_bpMGufdXbB4zWX1p-FwnkyOLpxyngyi6t2fIzaZvzD5QkfQsx6xkfjfBmkc1hcv-U6uj9S6QKdWD0nc_lwnqNv1x9vrz5XN18_fbn6cFP1VLa5IlY2trNdSzXrGtmI3jYtFYwYormVRpLOsm4YuATeQmEkN1JAWzPgVNQDPUfvd93D2i1m6I0vn5rVIbpFx3sVtFP_Vryb1BiOigDn0HJSFN48KMTwfTUpq8Wl3sxlLSasSdWtqFtghLUFrXe0jyGlaOzjHAJqc1HtLirYYnNRydL0-ukLH1v-2lYAugOplPxooroLa_Rla_-T_Q3Sgqy3</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2872804148</pqid></control><display><type>article</type><title>Feasibility and outcomes of living-donor liver transplantation utilizing the right hemi-liver graft with portal vein anatomical variations</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Shehta, Ahmed ; Elshobari, Mohamed ; Salah, Tarek ; Sultan, Ahmad M. ; Yasen, Amr ; Shiha, Usama ; El-Saadany, Mohamed ; Monier, Ahmed ; Said, Rami ; Habl, Mohamed S. ; Adly, Reham ; El Ged, Basma Abd Elmoaem ; Karam, Rasha ; Khaled, Reem ; El Razek, Hassan Magdy Abd ; Abdel-Khalek, Ehab E. ; Wahab, Mohamed Abdel</creator><creatorcontrib>Shehta, Ahmed ; Elshobari, Mohamed ; Salah, Tarek ; Sultan, Ahmad M. ; Yasen, Amr ; Shiha, Usama ; El-Saadany, Mohamed ; Monier, Ahmed ; Said, Rami ; Habl, Mohamed S. ; Adly, Reham ; El Ged, Basma Abd Elmoaem ; Karam, Rasha ; Khaled, Reem ; El Razek, Hassan Magdy Abd ; Abdel-Khalek, Ehab E. ; Wahab, Mohamed Abdel</creatorcontrib><description>Purpose
Portal vein (PV) reconstruction is a key factor for successful living-donor liver transplantation (LDLT). Anatomical variations of right PV (RPV) are encountered among potential donors.
Methods
To evaluate a single center experience of reconstruction techniques for the right hemi-liver grafts with PV variations during the period between May 2004 and 2022.
Results
A total of 915 recipients underwent LDLT, among them 52 (5.8%) had RPV anatomical variations. Type II PV was found in 7 cases (13.5%), which were reconstructed by direct venoplasty. Type III PV was found in 27 cases (51.9%). They were reconstructed by direct venoplasty in 2 cases (3.8%), Y graft interposition in 2 cases (3.8%), and in situ double PV anastomoses in 23 cases (44.2%). Type IV PV was found in 18 cases (34.6%) and was reconstructed by Y graft interposition in 9 cases (17.3%), and in situ double PV anastomoses in 9 cases (17.3%).
Early right posterior PV stenosis occurred in 2 recipients (3.8%). Early PV thrombosis occurred in 3 recipients (5.8%). The median follow-up duration was 54.5 months (4 – 185). The 1-, 3-, and 5-years survival rates were 91.9%, 86%, and 81.2%, respectively. Late PV stenosis occurred in 2 recipients (3.8%) and was managed conservatively.
Conclusion
Utilization of potential living donors with RPV anatomic variations may help to expand the donor pool. We found that direct venoplasty and in situ dual PV anastomoses techniques were safe, feasible, and associated with successful outcomes.</description><identifier>ISSN: 1435-2451</identifier><identifier>ISSN: 1435-2443</identifier><identifier>EISSN: 1435-2451</identifier><identifier>DOI: 10.1007/s00423-023-03115-9</identifier><identifier>PMID: 37792043</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Abdominal Surgery ; Anastomosis, Surgical ; Cardiac Surgery ; Constriction, Pathologic ; Feasibility Studies ; General Surgery ; Humans ; Liver - surgery ; Liver Transplantation - methods ; Living Donors ; Medicine ; Medicine & Public Health ; Portal Vein - surgery ; Retrospective Studies ; Thoracic Surgery ; Traumatic Surgery ; Vascular Surgery</subject><ispartof>Langenbeck's archives of surgery, 2023-10, Vol.408 (1), p.387-387, Article 387</ispartof><rights>The Author(s) 2023. corrected publication 2024</rights><rights>2023. The Author(s).</rights><rights>The Author(s) 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c398t-1f96fbfb83a4b6967cf683741e1a5f9e91bf4bdd590580a4b95e97082405372d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00423-023-03115-9$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00423-023-03115-9$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37792043$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shehta, Ahmed</creatorcontrib><creatorcontrib>Elshobari, Mohamed</creatorcontrib><creatorcontrib>Salah, Tarek</creatorcontrib><creatorcontrib>Sultan, Ahmad M.</creatorcontrib><creatorcontrib>Yasen, Amr</creatorcontrib><creatorcontrib>Shiha, Usama</creatorcontrib><creatorcontrib>El-Saadany, Mohamed</creatorcontrib><creatorcontrib>Monier, Ahmed</creatorcontrib><creatorcontrib>Said, Rami</creatorcontrib><creatorcontrib>Habl, Mohamed S.</creatorcontrib><creatorcontrib>Adly, Reham</creatorcontrib><creatorcontrib>El Ged, Basma Abd Elmoaem</creatorcontrib><creatorcontrib>Karam, Rasha</creatorcontrib><creatorcontrib>Khaled, Reem</creatorcontrib><creatorcontrib>El Razek, Hassan Magdy Abd</creatorcontrib><creatorcontrib>Abdel-Khalek, Ehab E.</creatorcontrib><creatorcontrib>Wahab, Mohamed Abdel</creatorcontrib><title>Feasibility and outcomes of living-donor liver transplantation utilizing the right hemi-liver graft with portal vein anatomical variations</title><title>Langenbeck's archives of surgery</title><addtitle>Langenbecks Arch Surg</addtitle><addtitle>Langenbecks Arch Surg</addtitle><description>Purpose
Portal vein (PV) reconstruction is a key factor for successful living-donor liver transplantation (LDLT). Anatomical variations of right PV (RPV) are encountered among potential donors.
Methods
To evaluate a single center experience of reconstruction techniques for the right hemi-liver grafts with PV variations during the period between May 2004 and 2022.
Results
A total of 915 recipients underwent LDLT, among them 52 (5.8%) had RPV anatomical variations. Type II PV was found in 7 cases (13.5%), which were reconstructed by direct venoplasty. Type III PV was found in 27 cases (51.9%). They were reconstructed by direct venoplasty in 2 cases (3.8%), Y graft interposition in 2 cases (3.8%), and in situ double PV anastomoses in 23 cases (44.2%). Type IV PV was found in 18 cases (34.6%) and was reconstructed by Y graft interposition in 9 cases (17.3%), and in situ double PV anastomoses in 9 cases (17.3%).
Early right posterior PV stenosis occurred in 2 recipients (3.8%). Early PV thrombosis occurred in 3 recipients (5.8%). The median follow-up duration was 54.5 months (4 – 185). The 1-, 3-, and 5-years survival rates were 91.9%, 86%, and 81.2%, respectively. Late PV stenosis occurred in 2 recipients (3.8%) and was managed conservatively.
Conclusion
Utilization of potential living donors with RPV anatomic variations may help to expand the donor pool. We found that direct venoplasty and in situ dual PV anastomoses techniques were safe, feasible, and associated with successful outcomes.</description><subject>Abdominal Surgery</subject><subject>Anastomosis, Surgical</subject><subject>Cardiac Surgery</subject><subject>Constriction, Pathologic</subject><subject>Feasibility Studies</subject><subject>General Surgery</subject><subject>Humans</subject><subject>Liver - surgery</subject><subject>Liver Transplantation - methods</subject><subject>Living Donors</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Portal Vein - surgery</subject><subject>Retrospective Studies</subject><subject>Thoracic Surgery</subject><subject>Traumatic Surgery</subject><subject>Vascular Surgery</subject><issn>1435-2451</issn><issn>1435-2443</issn><issn>1435-2451</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><recordid>eNp9kUFvFiEQhomxsbXtH_BgOHpZHRZYlpMxjVWTJl7qmbC7sEuzC5_Afqb-BH-1rFubevEwgck88w7Mi9ArAm8JgHiXAFhNK9iCEsIr-QydEUZ5VTNOnj-5n6KXKd0BQCMke4FOqRCyBkbP0K9ro5Pr3OzyPdZ-wGHNfVhMwsHi2R2dH6sh-BC3xESco_bpMGufdXbB4zWX1p-FwnkyOLpxyngyi6t2fIzaZvzD5QkfQsx6xkfjfBmkc1hcv-U6uj9S6QKdWD0nc_lwnqNv1x9vrz5XN18_fbn6cFP1VLa5IlY2trNdSzXrGtmI3jYtFYwYormVRpLOsm4YuATeQmEkN1JAWzPgVNQDPUfvd93D2i1m6I0vn5rVIbpFx3sVtFP_Vryb1BiOigDn0HJSFN48KMTwfTUpq8Wl3sxlLSasSdWtqFtghLUFrXe0jyGlaOzjHAJqc1HtLirYYnNRydL0-ukLH1v-2lYAugOplPxooroLa_Rla_-T_Q3Sgqy3</recordid><startdate>20231004</startdate><enddate>20231004</enddate><creator>Shehta, Ahmed</creator><creator>Elshobari, Mohamed</creator><creator>Salah, Tarek</creator><creator>Sultan, Ahmad M.</creator><creator>Yasen, Amr</creator><creator>Shiha, Usama</creator><creator>El-Saadany, Mohamed</creator><creator>Monier, Ahmed</creator><creator>Said, Rami</creator><creator>Habl, Mohamed S.</creator><creator>Adly, Reham</creator><creator>El Ged, Basma Abd Elmoaem</creator><creator>Karam, Rasha</creator><creator>Khaled, Reem</creator><creator>El Razek, Hassan Magdy Abd</creator><creator>Abdel-Khalek, Ehab E.</creator><creator>Wahab, Mohamed Abdel</creator><general>Springer Berlin Heidelberg</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20231004</creationdate><title>Feasibility and outcomes of living-donor liver transplantation utilizing the right hemi-liver graft with portal vein anatomical variations</title><author>Shehta, Ahmed ; Elshobari, Mohamed ; Salah, Tarek ; Sultan, Ahmad M. ; Yasen, Amr ; Shiha, Usama ; El-Saadany, Mohamed ; Monier, Ahmed ; Said, Rami ; Habl, Mohamed S. ; Adly, Reham ; El Ged, Basma Abd Elmoaem ; Karam, Rasha ; Khaled, Reem ; El Razek, Hassan Magdy Abd ; Abdel-Khalek, Ehab E. ; Wahab, Mohamed Abdel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c398t-1f96fbfb83a4b6967cf683741e1a5f9e91bf4bdd590580a4b95e97082405372d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Abdominal Surgery</topic><topic>Anastomosis, Surgical</topic><topic>Cardiac Surgery</topic><topic>Constriction, Pathologic</topic><topic>Feasibility Studies</topic><topic>General Surgery</topic><topic>Humans</topic><topic>Liver - surgery</topic><topic>Liver Transplantation - methods</topic><topic>Living Donors</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Portal Vein - surgery</topic><topic>Retrospective Studies</topic><topic>Thoracic Surgery</topic><topic>Traumatic Surgery</topic><topic>Vascular Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shehta, Ahmed</creatorcontrib><creatorcontrib>Elshobari, Mohamed</creatorcontrib><creatorcontrib>Salah, Tarek</creatorcontrib><creatorcontrib>Sultan, Ahmad M.</creatorcontrib><creatorcontrib>Yasen, Amr</creatorcontrib><creatorcontrib>Shiha, Usama</creatorcontrib><creatorcontrib>El-Saadany, Mohamed</creatorcontrib><creatorcontrib>Monier, Ahmed</creatorcontrib><creatorcontrib>Said, Rami</creatorcontrib><creatorcontrib>Habl, Mohamed S.</creatorcontrib><creatorcontrib>Adly, Reham</creatorcontrib><creatorcontrib>El Ged, Basma Abd Elmoaem</creatorcontrib><creatorcontrib>Karam, Rasha</creatorcontrib><creatorcontrib>Khaled, Reem</creatorcontrib><creatorcontrib>El Razek, Hassan Magdy Abd</creatorcontrib><creatorcontrib>Abdel-Khalek, Ehab E.</creatorcontrib><creatorcontrib>Wahab, Mohamed Abdel</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Langenbeck's archives of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shehta, Ahmed</au><au>Elshobari, Mohamed</au><au>Salah, Tarek</au><au>Sultan, Ahmad M.</au><au>Yasen, Amr</au><au>Shiha, Usama</au><au>El-Saadany, Mohamed</au><au>Monier, Ahmed</au><au>Said, Rami</au><au>Habl, Mohamed S.</au><au>Adly, Reham</au><au>El Ged, Basma Abd Elmoaem</au><au>Karam, Rasha</au><au>Khaled, Reem</au><au>El Razek, Hassan Magdy Abd</au><au>Abdel-Khalek, Ehab E.</au><au>Wahab, Mohamed Abdel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Feasibility and outcomes of living-donor liver transplantation utilizing the right hemi-liver graft with portal vein anatomical variations</atitle><jtitle>Langenbeck's archives of surgery</jtitle><stitle>Langenbecks Arch Surg</stitle><addtitle>Langenbecks Arch Surg</addtitle><date>2023-10-04</date><risdate>2023</risdate><volume>408</volume><issue>1</issue><spage>387</spage><epage>387</epage><pages>387-387</pages><artnum>387</artnum><issn>1435-2451</issn><issn>1435-2443</issn><eissn>1435-2451</eissn><abstract>Purpose
Portal vein (PV) reconstruction is a key factor for successful living-donor liver transplantation (LDLT). Anatomical variations of right PV (RPV) are encountered among potential donors.
Methods
To evaluate a single center experience of reconstruction techniques for the right hemi-liver grafts with PV variations during the period between May 2004 and 2022.
Results
A total of 915 recipients underwent LDLT, among them 52 (5.8%) had RPV anatomical variations. Type II PV was found in 7 cases (13.5%), which were reconstructed by direct venoplasty. Type III PV was found in 27 cases (51.9%). They were reconstructed by direct venoplasty in 2 cases (3.8%), Y graft interposition in 2 cases (3.8%), and in situ double PV anastomoses in 23 cases (44.2%). Type IV PV was found in 18 cases (34.6%) and was reconstructed by Y graft interposition in 9 cases (17.3%), and in situ double PV anastomoses in 9 cases (17.3%).
Early right posterior PV stenosis occurred in 2 recipients (3.8%). Early PV thrombosis occurred in 3 recipients (5.8%). The median follow-up duration was 54.5 months (4 – 185). The 1-, 3-, and 5-years survival rates were 91.9%, 86%, and 81.2%, respectively. Late PV stenosis occurred in 2 recipients (3.8%) and was managed conservatively.
Conclusion
Utilization of potential living donors with RPV anatomic variations may help to expand the donor pool. We found that direct venoplasty and in situ dual PV anastomoses techniques were safe, feasible, and associated with successful outcomes.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>37792043</pmid><doi>10.1007/s00423-023-03115-9</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1435-2451 |
| ispartof | Langenbeck's archives of surgery, 2023-10, Vol.408 (1), p.387-387, Article 387 |
| issn | 1435-2451 1435-2443 1435-2451 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10550851 |
| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Abdominal Surgery Anastomosis, Surgical Cardiac Surgery Constriction, Pathologic Feasibility Studies General Surgery Humans Liver - surgery Liver Transplantation - methods Living Donors Medicine Medicine & Public Health Portal Vein - surgery Retrospective Studies Thoracic Surgery Traumatic Surgery Vascular Surgery |
| title | Feasibility and outcomes of living-donor liver transplantation utilizing the right hemi-liver graft with portal vein anatomical variations |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T16%3A14%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Feasibility%20and%20outcomes%20of%20living-donor%20liver%20transplantation%20utilizing%20the%20right%20hemi-liver%20graft%20with%20portal%20vein%20anatomical%20variations&rft.jtitle=Langenbeck's%20archives%20of%20surgery&rft.au=Shehta,%20Ahmed&rft.date=2023-10-04&rft.volume=408&rft.issue=1&rft.spage=387&rft.epage=387&rft.pages=387-387&rft.artnum=387&rft.issn=1435-2451&rft.eissn=1435-2451&rft_id=info:doi/10.1007/s00423-023-03115-9&rft_dat=%3Cproquest_pubme%3E2872804148%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2872804148&rft_id=info:pmid/37792043&rfr_iscdi=true |