Comparison of the Arterial PaCO 2 Values and ETCO 2 Values Measured with Sidestream Capnography in Patients with a Prediagnosis of COPD Exacerbation
Background Aim of this study is to investigate whether end-tidal carbon dioxide (ETCO 2 ) values can be used instead of partial pressure of carbon dioxide (PaCO 2 ) values in guiding treatment, and determining treatment benefits in patients that received a pre-diagnosis of chronic obstructive pulmo...
Gespeichert in:
| Veröffentlicht in: | Avicenna journal of medicine 2023-10, Vol.13 (3), p.182-186 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 186 |
|---|---|
| container_issue | 3 |
| container_start_page | 182 |
| container_title | Avicenna journal of medicine |
| container_volume | 13 |
| creator | İşat, Gökhan Cimilli Öztürk, Tuba Ecmel Onur, Özge Özdemir, Serdar Ünal Akoğlu, Ebru Tokgöz Akyıl, Fatma Kuzu Okur, Hacer |
| description | Background
Aim of this study is to investigate whether end-tidal carbon dioxide (ETCO
2
) values can be used instead of partial pressure of carbon dioxide (PaCO
2
) values in guiding treatment, and determining treatment benefits in patients that received a pre-diagnosis of chronic obstructive pulmonary disease (COPD) exacerbation at the emergency department.
Methods
This observational prospective study was conducted with patients who presented to the emergency department with the complaint of shortness of breath and were diagnosed with COPD exacerbation. ETCO
2
was measured with the sidestream method during blood gas analysis in patients with indications for this analysis. Measurements were repeated at hour 1 after treatment.
Results
The study included a total of 121 cases. There was a positive correlation between the PaCO
2
and ETCO
2
values measured before and after treatment (
r
= 0.736,
p
|
| doi_str_mv | 10.1055/s-0043-1771179 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10550360</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2874261093</sourcerecordid><originalsourceid>FETCH-LOGICAL-p1279-a5db9d5650e720f868fabff9494412e4e052022351be06f44650fa8521983a203</originalsourceid><addsrcrecordid>eNpVUMtOxDAMrBBIIODKOUcuBSdNmvaEUHlKoF2Jx7Vyt-5uUJuUpMvjP_hgsoID-GLLHs_YkyRHHE44KHUaUgCZpVxrznW5lewJIctUylxub-qMp6A17CaHIbxADF1wDcVe8lW5YURvgrPMdWxaETv3E3mDPZtjNWOCPWO_psDQtuzy8W_nnjCsPbXs3Uwr9mBaCpMnHFiFo3VLj-PqkxkbeSZDdgo_OGTzuGNwaV0wYSNazeYX7PIDF-SbCHX2INnpsA90-Jv3k6erKH2T3s2ub6vzu3TkQpcpqrYpW5UrIC2gK_Kiw6brSllKyQVJAiUg_q54Q5B30QwFHRZK8LLIUEC2n5z98I7rZqB2EY_02NejNwP6z9qhqf9PrFnVS_dWbyyHLN8wHP8yePcaPZnqwYQF9T1acutQi0JLkXMos-wbt9yAig</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2874261093</pqid></control><display><type>article</type><title>Comparison of the Arterial PaCO 2 Values and ETCO 2 Values Measured with Sidestream Capnography in Patients with a Prediagnosis of COPD Exacerbation</title><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>Thieme Connect Journals Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>İşat, Gökhan ; Cimilli Öztürk, Tuba ; Ecmel Onur, Özge ; Özdemir, Serdar ; Ünal Akoğlu, Ebru ; Tokgöz Akyıl, Fatma ; Kuzu Okur, Hacer</creator><creatorcontrib>İşat, Gökhan ; Cimilli Öztürk, Tuba ; Ecmel Onur, Özge ; Özdemir, Serdar ; Ünal Akoğlu, Ebru ; Tokgöz Akyıl, Fatma ; Kuzu Okur, Hacer</creatorcontrib><description>Background
Aim of this study is to investigate whether end-tidal carbon dioxide (ETCO
2
) values can be used instead of partial pressure of carbon dioxide (PaCO
2
) values in guiding treatment, and determining treatment benefits in patients that received a pre-diagnosis of chronic obstructive pulmonary disease (COPD) exacerbation at the emergency department.
Methods
This observational prospective study was conducted with patients who presented to the emergency department with the complaint of shortness of breath and were diagnosed with COPD exacerbation. ETCO
2
was measured with the sidestream method during blood gas analysis in patients with indications for this analysis. Measurements were repeated at hour 1 after treatment.
Results
The study included a total of 121 cases. There was a positive correlation between the PaCO
2
and ETCO
2
values measured before and after treatment (
r
= 0.736,
p
< 0.01 and
r
= 0.883,
p
< 0.01, respectively). High ETCO
2
values were accompanied by high PaCO
2
values. When the measurements before and after treatment were evaluated using the Bland–Altman method, most of the result were within the limits of agreement (−4.9 and +31.4/− 2.6 and +9.4), with mean differences being calculated as 13.2 and 8.4, respectively.
Conclusions
Although ETCO
2
and PaCO
2
were statistically consistent according to the results of our study, due to the high averages of differences between these two parameters, the ETCO
2
value has limited clinical use in COPD cases compared to PaCO
2
. However, high ETCO
2
values may indicate that noninvasive mechanical ventilation should be included in the treatment of COPD cases without waiting for the results of blood gas analysis, and they can also be when needed for inpatient treatment.</description><identifier>ISSN: 2231-0770</identifier><identifier>EISSN: 2249-4464</identifier><identifier>DOI: 10.1055/s-0043-1771179</identifier><language>eng</language><publisher>A-12, 2nd Floor, Sector 2, Noida-201301 UP, India: Thieme Medical and Scientific Publishers Pvt. Ltd</publisher><subject>Original</subject><ispartof>Avicenna journal of medicine, 2023-10, Vol.13 (3), p.182-186</ispartof><rights>The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( ) 2023 The Author(s).</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550360/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550360/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids></links><search><creatorcontrib>İşat, Gökhan</creatorcontrib><creatorcontrib>Cimilli Öztürk, Tuba</creatorcontrib><creatorcontrib>Ecmel Onur, Özge</creatorcontrib><creatorcontrib>Özdemir, Serdar</creatorcontrib><creatorcontrib>Ünal Akoğlu, Ebru</creatorcontrib><creatorcontrib>Tokgöz Akyıl, Fatma</creatorcontrib><creatorcontrib>Kuzu Okur, Hacer</creatorcontrib><title>Comparison of the Arterial PaCO 2 Values and ETCO 2 Values Measured with Sidestream Capnography in Patients with a Prediagnosis of COPD Exacerbation</title><title>Avicenna journal of medicine</title><description>Background
Aim of this study is to investigate whether end-tidal carbon dioxide (ETCO
2
) values can be used instead of partial pressure of carbon dioxide (PaCO
2
) values in guiding treatment, and determining treatment benefits in patients that received a pre-diagnosis of chronic obstructive pulmonary disease (COPD) exacerbation at the emergency department.
Methods
This observational prospective study was conducted with patients who presented to the emergency department with the complaint of shortness of breath and were diagnosed with COPD exacerbation. ETCO
2
was measured with the sidestream method during blood gas analysis in patients with indications for this analysis. Measurements were repeated at hour 1 after treatment.
Results
The study included a total of 121 cases. There was a positive correlation between the PaCO
2
and ETCO
2
values measured before and after treatment (
r
= 0.736,
p
< 0.01 and
r
= 0.883,
p
< 0.01, respectively). High ETCO
2
values were accompanied by high PaCO
2
values. When the measurements before and after treatment were evaluated using the Bland–Altman method, most of the result were within the limits of agreement (−4.9 and +31.4/− 2.6 and +9.4), with mean differences being calculated as 13.2 and 8.4, respectively.
Conclusions
Although ETCO
2
and PaCO
2
were statistically consistent according to the results of our study, due to the high averages of differences between these two parameters, the ETCO
2
value has limited clinical use in COPD cases compared to PaCO
2
. However, high ETCO
2
values may indicate that noninvasive mechanical ventilation should be included in the treatment of COPD cases without waiting for the results of blood gas analysis, and they can also be when needed for inpatient treatment.</description><subject>Original</subject><issn>2231-0770</issn><issn>2249-4464</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNpVUMtOxDAMrBBIIODKOUcuBSdNmvaEUHlKoF2Jx7Vyt-5uUJuUpMvjP_hgsoID-GLLHs_YkyRHHE44KHUaUgCZpVxrznW5lewJIctUylxub-qMp6A17CaHIbxADF1wDcVe8lW5YURvgrPMdWxaETv3E3mDPZtjNWOCPWO_psDQtuzy8W_nnjCsPbXs3Uwr9mBaCpMnHFiFo3VLj-PqkxkbeSZDdgo_OGTzuGNwaV0wYSNazeYX7PIDF-SbCHX2INnpsA90-Jv3k6erKH2T3s2ub6vzu3TkQpcpqrYpW5UrIC2gK_Kiw6brSllKyQVJAiUg_q54Q5B30QwFHRZK8LLIUEC2n5z98I7rZqB2EY_02NejNwP6z9qhqf9PrFnVS_dWbyyHLN8wHP8yePcaPZnqwYQF9T1acutQi0JLkXMos-wbt9yAig</recordid><startdate>20231004</startdate><enddate>20231004</enddate><creator>İşat, Gökhan</creator><creator>Cimilli Öztürk, Tuba</creator><creator>Ecmel Onur, Özge</creator><creator>Özdemir, Serdar</creator><creator>Ünal Akoğlu, Ebru</creator><creator>Tokgöz Akyıl, Fatma</creator><creator>Kuzu Okur, Hacer</creator><general>Thieme Medical and Scientific Publishers Pvt. Ltd</general><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20231004</creationdate><title>Comparison of the Arterial PaCO 2 Values and ETCO 2 Values Measured with Sidestream Capnography in Patients with a Prediagnosis of COPD Exacerbation</title><author>İşat, Gökhan ; Cimilli Öztürk, Tuba ; Ecmel Onur, Özge ; Özdemir, Serdar ; Ünal Akoğlu, Ebru ; Tokgöz Akyıl, Fatma ; Kuzu Okur, Hacer</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p1279-a5db9d5650e720f868fabff9494412e4e052022351be06f44650fa8521983a203</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Original</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>İşat, Gökhan</creatorcontrib><creatorcontrib>Cimilli Öztürk, Tuba</creatorcontrib><creatorcontrib>Ecmel Onur, Özge</creatorcontrib><creatorcontrib>Özdemir, Serdar</creatorcontrib><creatorcontrib>Ünal Akoğlu, Ebru</creatorcontrib><creatorcontrib>Tokgöz Akyıl, Fatma</creatorcontrib><creatorcontrib>Kuzu Okur, Hacer</creatorcontrib><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Avicenna journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>İşat, Gökhan</au><au>Cimilli Öztürk, Tuba</au><au>Ecmel Onur, Özge</au><au>Özdemir, Serdar</au><au>Ünal Akoğlu, Ebru</au><au>Tokgöz Akyıl, Fatma</au><au>Kuzu Okur, Hacer</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of the Arterial PaCO 2 Values and ETCO 2 Values Measured with Sidestream Capnography in Patients with a Prediagnosis of COPD Exacerbation</atitle><jtitle>Avicenna journal of medicine</jtitle><date>2023-10-04</date><risdate>2023</risdate><volume>13</volume><issue>3</issue><spage>182</spage><epage>186</epage><pages>182-186</pages><issn>2231-0770</issn><eissn>2249-4464</eissn><abstract>Background
Aim of this study is to investigate whether end-tidal carbon dioxide (ETCO
2
) values can be used instead of partial pressure of carbon dioxide (PaCO
2
) values in guiding treatment, and determining treatment benefits in patients that received a pre-diagnosis of chronic obstructive pulmonary disease (COPD) exacerbation at the emergency department.
Methods
This observational prospective study was conducted with patients who presented to the emergency department with the complaint of shortness of breath and were diagnosed with COPD exacerbation. ETCO
2
was measured with the sidestream method during blood gas analysis in patients with indications for this analysis. Measurements were repeated at hour 1 after treatment.
Results
The study included a total of 121 cases. There was a positive correlation between the PaCO
2
and ETCO
2
values measured before and after treatment (
r
= 0.736,
p
< 0.01 and
r
= 0.883,
p
< 0.01, respectively). High ETCO
2
values were accompanied by high PaCO
2
values. When the measurements before and after treatment were evaluated using the Bland–Altman method, most of the result were within the limits of agreement (−4.9 and +31.4/− 2.6 and +9.4), with mean differences being calculated as 13.2 and 8.4, respectively.
Conclusions
Although ETCO
2
and PaCO
2
were statistically consistent according to the results of our study, due to the high averages of differences between these two parameters, the ETCO
2
value has limited clinical use in COPD cases compared to PaCO
2
. However, high ETCO
2
values may indicate that noninvasive mechanical ventilation should be included in the treatment of COPD cases without waiting for the results of blood gas analysis, and they can also be when needed for inpatient treatment.</abstract><cop>A-12, 2nd Floor, Sector 2, Noida-201301 UP, India</cop><pub>Thieme Medical and Scientific Publishers Pvt. Ltd</pub><doi>10.1055/s-0043-1771179</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2231-0770 |
| ispartof | Avicenna journal of medicine, 2023-10, Vol.13 (3), p.182-186 |
| issn | 2231-0770 2249-4464 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10550360 |
| source | DOAJ Directory of Open Access Journals; PubMed Central Open Access; Thieme Connect Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Original |
| title | Comparison of the Arterial PaCO 2 Values and ETCO 2 Values Measured with Sidestream Capnography in Patients with a Prediagnosis of COPD Exacerbation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T10%3A56%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparison%20of%20the%20Arterial%20PaCO%202%20Values%20and%20ETCO%202%20Values%20Measured%20with%20Sidestream%20Capnography%20in%20Patients%20with%20a%20Prediagnosis%20of%20COPD%20Exacerbation&rft.jtitle=Avicenna%20journal%20of%20medicine&rft.au=%C4%B0%C5%9Fat,%20G%C3%B6khan&rft.date=2023-10-04&rft.volume=13&rft.issue=3&rft.spage=182&rft.epage=186&rft.pages=182-186&rft.issn=2231-0770&rft.eissn=2249-4464&rft_id=info:doi/10.1055/s-0043-1771179&rft_dat=%3Cproquest_pubme%3E2874261093%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2874261093&rft_id=info:pmid/&rfr_iscdi=true |