Can physiologic colonic [18F]FDG uptake in PET/CT imaging predict response to immunotherapy in metastatic melanoma?

Aim The development of biomarkers that can reliably and early predict response to immune checkpoint inhibitors (ICIs) is crucial in melanoma. In recent years, the gut microbiome has emerged as an important regulator of immunotherapy response, which may, moreover, serve as a surrogate marker and prog...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2023-10, Vol.50 (12), p.3709-3722
Hauptverfasser:	Sachpekidis, Christos, Stein-Thoeringer, Christoph K., Kopp-Schneider, Annette, Weru, Vivienn, Dimitrakopoulou-Strauss, Antonia, Hassel, Jessica C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Bone marrow Cardiology Colitis Colon Computed tomography Correlation Data analysis Digestive system Disease control Fluorine isotopes Glucose metabolism Glycolysis Health services Homeostasis Imaging Immune checkpoint inhibitors Immunotherapy Intestinal microflora Lipopolysaccharides Liver Mathematical analysis Medical prognosis Medicine Medicine & Public Health Melanoma Metastases Metastasis Microbiomes Microbiota Multivariate analysis Nuclear Medicine Oncology Organs Original Original Article Orthopedics Parameters Patients Positron emission Radiology Spleen Survival
Online-Zugang:	Volltext
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