Seasonal Malaria Chemoprevention Drug Levels and Drug Resistance Markers in Children With or Without Malaria in Burkina Faso: A Case-Control Study

Abstract Background Despite scale-up of seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine (SP-AQ) in children 3–59 months of age in Burkina Faso, malaria incidence remains high, raising concerns regarding SMC effectiveness and selection of drug resistance. Using a...

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Veröffentlicht in:	The Journal of infectious diseases 2023-10, Vol.228 (7), p.926-935
Hauptverfasser:	Roh, Michelle E, Zongo, Issaka, Haro, Alassane, Huang, Liusheng, Somé, Anyirékun Fabrice, Yerbanga, Rakiswendé Serge, Conrad, Melissa D, Wallender, Erika, Legac, Jennifer, Aweeka, Francesca, Ouédraogo, Jean-Bosco, Rosenthal, Philip J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amodiaquine Amodiaquine - therapeutic use Antimalarial agents Antimalarials - pharmacology Antimalarials - therapeutic use Burkina Faso - epidemiology Case-Control Studies Chemoprevention - methods Child Child, Preschool Children Drug Combinations Drug development Drug Resistance Humans Infant Major Malaria Malaria - drug therapy Malaria - epidemiology Malaria - prevention & control Pyrimethamine Seasons Sulfadoxine Sulfadoxine - therapeutic use
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