Diffusion-enhanced characterization of 3D chromatin structure reveals its linkage to gene regulatory networks and the interactome

The interactome networks at the DNA, RNA, and protein levels are crucial for cellular functions, and the diverse variations of these networks are heavily involved in the establishment of different cell states. We have developed a diffusion-based method, Hi-C to geometry (C G), to obtain reliable geo...

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Veröffentlicht in:	Genome research 2023-08, Vol.33 (8), p.1354-1368
Hauptverfasser:	He, Yueying, Xue, Yue, Wang, Jingyao, Huang, Yupeng, Liu, Lu, Huang, Yanyi, Gao, Yi Qin
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatin Chromatin - genetics Chromosomes DNA Gene Expression Regulation Gene fusion Gene regulation Gene Regulatory Networks Genomics Methods Protein interaction Proteins
Online-Zugang:	Volltext
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