Transgenerational effects of developmental neurotoxicity induced by exposure to a no-observed-adverse-effect level (NOAEL) of neonicotinoid pesticide clothianidin

Neonicotinoid pesticides (NNs) transfer rapidly from mother to offspring, which exhibit neurobehavioral effects. However, no studies have investigated NNs’ transgenerational effects. We exposed F0 generation mice (mothers) to a no-observed-adverse-effect level (NOAEL) of clothianidin (CLO) during ge...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2023, pp.23-0101
Hauptverfasser:	SHODA, Asuka, MURATA, Midori, KIMURA, Mako, HARA, Yukako, YONOICHI, Sakura, ISHIDA, Yuya, MANTANI, Youhei, YOKOYAMA, Toshifumi, HIRANO, Tetsushi, IKENAKA, Yoshinori, HOSHI, Nobuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anxiety behavioral test Birth weight Body weight developmental stage Female fetal and lactational exposure Guanidines - toxicity Lactation Locomotor activity Mice neonicotinoid Neonicotinoids - toxicity Neurotoxicity No-Observed-Adverse-Effect Level Offspring Pesticides Pesticides - toxicity Prenatal Exposure Delayed Effects - chemically induced Prenatal Exposure Delayed Effects - veterinary Toxicology transgenerational toxicity
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