Coarctation of the Aorta: Modern Paradigms Across the Lifespan

While coarctation of the aorta varies greatly in both severity and age at presentation, all patients are at increased risk of hypertension both before and after repair. Despite advances in knowledge about genetic etiologies, pathophysiologic mechanisms, and optimal repair strategies, patients with r...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2023-10, Vol.80 (10), p.1970-1979
Hauptverfasser:	Salciccioli, Katherine B., Zachariah, Justin P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aorta Aortic Coarctation - surgery Ductus Arteriosus Humans Hypertension - etiology Longevity
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container_end_page	1979
container_issue	10
container_start_page	1970
container_title	Hypertension (Dallas, Tex. 1979)
container_volume	80
creator	Salciccioli, Katherine B. Zachariah, Justin P.
description	While coarctation of the aorta varies greatly in both severity and age at presentation, all patients are at increased risk of hypertension both before and after repair. Despite advances in knowledge about genetic etiologies, pathophysiologic mechanisms, and optimal repair strategies, patients with repaired coarctation of the aorta remain at increased risk of acquired cardiovascular disease. The aims of this review are to describe the management of coarctation of the aorta at all ages before and after repair, highlight pathophysiologic mechanisms of hypertension, and review long-term follow-up considerations.
doi_str_mv	10.1161/HYPERTENSIONAHA.123.19454
format	Article
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source	MEDLINE; American Heart Association Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects	Aorta Aortic Coarctation - surgery Ductus Arteriosus Humans Hypertension - etiology Longevity
title	Coarctation of the Aorta: Modern Paradigms Across the Lifespan
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