Total Synthesis and Biological Investigation of Mindapyrroles A and B

In the search for antibacterial compounds that can overcome drug resistant species, molecules that enact novel or polypharmacological mechanisms of action (MoA) are needed. As a preliminary foray into molecules of this background, the total synthesis of mindapyrroles A and B was undertaken leveragin...

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Veröffentlicht in:	ChemMedChem 2023-09, Vol.18 (18), p.e202300235-e202300235
Hauptverfasser:	Allen, Ryan A, Wuest, William M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antibacterial materials Biomimetics Chemical synthesis Drug resistance Membrane potential Methicillin-Resistant Staphylococcus aureus Microbial Sensitivity Tests Minimum inhibitory concentration Monomers Phenols Pyrroles - pharmacology Staphylococcus aureus
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