A Systematic Review and Pooled Analysis of Hypothesized versus Observed Effect Sizes in Early Phase Cancer Prevention Clinical Trials

Early phase cancer prevention trials are designed to demonstrate safety, tolerability, feasibility, and signals of efficacy of preventive agents. Yet it is often observed that many trials fail to detect intervention effects. We conducted a systematic review and pooled analyses of recently completed...

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Veröffentlicht in:	Cancer prevention research (Philadelphia, Pa.) Pa.), 2023-08, Vol.16 (8), p.471-478
Hauptverfasser:	Eickhoff, Jens, Zaborek, Jen, Chen, Guanhua, Sahasrabuddhe, Vikrant V, Ford, Leslie G, Szabo, Eva, Kim, KyungMann
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemoprevention Humans Neoplasms - prevention & control Research Design
Online-Zugang:	Volltext
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