Diverse modes of regulating methyltransferase activity by histone ubiquitination

Post-translational modification of histones plays a central role in regulating transcription. Methylation of histone H3 at lysines 4 (H3K4) and 79 (H3K79) play roles in activating transcription whereas methylation of H3K27 is a repressive mark. These modifications, in turn, depend upon prior monoubi...

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Veröffentlicht in:	Current opinion in structural biology 2023-10, Vol.82, p.102649-102649, Article 102649
Hauptverfasser:	Fields, James K., Hicks, Chad W., Wolberger, Cynthia
Format:	Artikel
Sprache:	eng
Schlagworte:	Histones - metabolism Humans Methylation Protein Processing, Post-Translational Saccharomyces cerevisiae - metabolism Ubiquitination
Online-Zugang:	Volltext
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