Association between AHR Expression and Immune Dysregulation in Pancreatic Ductal Adenocarcinoma: Insights from Comprehensive Immune Profiling of Peripheral Blood Mononuclear Cells

Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), has an immune suppressive environment that allows tumour cells to evade the immune system. The aryl-hydrocarbon receptor (AHR) is a transcription factor that can be activated by certain exo/endo ligands, including kynurenine (K...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancers 2023-09, Vol.15 (18), p.4639
Hauptverfasser:	Bartkeviciene, Arenida, Jasukaitiene, Aldona, Zievyte, Inga, Stukas, Darius, Ivanauskiene, Sandra, Urboniene, Daiva, Maimets, Toivo, Jaudzems, Kristaps, Vitkauskiene, Astra, Matthews, Jason, Dambrauskas, Zilvinas, Gulbinas, Antanas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Age AhR gene Apoptosis Brain cancer Cytokines Gene expression Immune response Immunology Immunotherapy Interleukins Leukocytes (mononuclear) Ligands Lymphocytes Melanoma Monocytes Nitric oxide Pancreatic cancer Patients PD-1 protein Peripheral blood mononuclear cells Phagocytosis Tryptophan Tumor necrosis factor-TNF Tumors Womens health
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!