A dendritic/tumor fusion cell vaccine enhances efficacy of nanobody-based CAR-T cells against solid tumor

Background: Chimeric antigen receptor (CAR) T-cell therapy is practical in treating cancers of hematopoietic origin, but of that in solid tumors compromises efficacy for the loss of the antigen recognized by the CAR. However, dendritic cell (DC)/tumor fusion vaccines present a spectrum of known or u...

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Veröffentlicht in:Theranostics 2023-01, Vol.13 (14), p.5099-5113
Hauptverfasser: Sun, Shuyang, Ding, Ziqiang, Gao, Li, Hammock, Bruce D., Huang, Xianing, Xu, Zhi Ping, Wang, Xuan, Cheng, Qihong, Mo, Fengzhen, Shi, Wei, Xie, Shenxia, Liu, Aiqun, Li, Haixia, Yang, Xiaomei, Lu, Xiaoling
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Sprache:eng
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