Mechanisms of Resistance to Small Molecules in Acute Myeloid Leukemia

In recent years, great progress has been made in the therapy of AML by targeting cellular processes associated with specific molecular features of the disease. Various small molecules inhibiting FLT3, IDH1/IDH2, and BCL2 have already gained approval from the respective authorities and are essential...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cancers 2023-09, Vol.15 (18), p.4573
Hauptverfasser:	Lang, Tonio Johannes Lukas, Damm, Frederik, Bullinger, Lars, Frick, Mareike
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Antimitotic agents Antineoplastic agents Bcl-2 protein Bone marrow Chemotherapy Cloning Diseases Health aspects Kinases Mutation Patients Proteins Relapse Review
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!