HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma

Asbestos is the main cause of malignant mesothelioma. Previous studies have linked asbestos-induced mesothelioma to the release of HMGB1 from the nucleus to the cytoplasm, and from the cytoplasm to the extracellular space. In the cytoplasm, HMGB1 induces autophagy impairing asbestos-induced cell dea...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2023-09, Vol.120 (39), p.e2307999120
Hauptverfasser: Suarez, Joelle S, Novelli, Flavia, Goto, Keisuke, Ehara, Michiko, Steele, Mika, Kim, Jin-Hee, Zolondick, Alicia A, Xue, Jiaming, Xu, Ronghui, Saito, Mai, Pastorino, Sandra, Minaai, Michael, Takanishi, Yasutaka, Emi, Mitsuru, Pagano, Ian, Wakeham, Andrew, Berger, Thorsten, Pass, Harvey I, Gaudino, Giovanni, Mak, Tak W, Carbone, Michele, Yang, Haining
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Sprache:eng
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