HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma
Asbestos is the main cause of malignant mesothelioma. Previous studies have linked asbestos-induced mesothelioma to the release of HMGB1 from the nucleus to the cytoplasm, and from the cytoplasm to the extracellular space. In the cytoplasm, HMGB1 induces autophagy impairing asbestos-induced cell dea...
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Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 2023-09, Vol.120 (39), p.e2307999120 |
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