The endoplasmic reticulum–localized enzyme zDHHC6 mediates S-acylation of short transmembrane constructs from multiple type I and II membrane proteins

In this study, we investigated the S-acylation of two host cell proteins important for viral infection: TMPRSS2 (transmembrane serine protease 2), which cleaves severe acute respiratory syndrome coronavirus 2 spike to facilitate viral entry, and bone marrow stromal antigen 2, a general viral restric...

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Veröffentlicht in:	The Journal of biological chemistry 2023-10, Vol.299 (10), p.105201-105201, Article 105201
Hauptverfasser:	Salaun, Christine, Tomkinson, Nicholas C.O., Chamberlain, Luke H.
Format:	Artikel
Sprache:	eng
Schlagworte:	endoplasmic reticulum mPEG-Click palmitoylation S-acylation transmembrane zDHHC enzymes zDHHC6
Online-Zugang:	Volltext
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