Regulation of Axon Guidance by Slit2 and Netrin-1 Signaling in the Lacrimal Gland of Aqp5 Knockout Mice

Dry eye disease (DED) is multifactorial and associated with nerve abnormalities. We explored an Aquaporin 5 (AQP5)-deficiency-induced JunB activation mechanism, which causes abnormal lacrimal gland (LG) nerve distribution through Slit2 upregulation and Netrin-1 repression.PurposeDry eye disease (DED...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2023-09, Vol.64 (12), p.27
Hauptverfasser:	Bai, Ying, Di, Guohu, Ge, Huanhuan, Li, Bin, Zhang, Kaier, Zhang, Di, Wang, Dianqiang, Chen, Peng
Format:	Artikel
Sprache:	eng
Schlagworte:	Visual Neuroscience
Online-Zugang:	Volltext
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